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PMID: 6324120 Published · ppublish English Journal Article

The complete nucleotide sequence of the RNA coding for the primary translation product of foot and mouth disease virus.

Nucleic acids research ·Vol. 12 ·No. 5 ·1984-03-12 ·Pages 2461-72

Carroll AR, Rowlands DJ, Clarke BE

Abstract

The complete nucleotide sequence of the coding region of foot and mouth disease virus RNA (strain A1061) is presented. The sequence extends from the primary initiation site, approximately 1200 nucleotide from the 5' end of the genome, in an open translational reading frame of 6,999 nucleotides to a termination codon 93 nucleotides from the 3' terminal poly (A). Available amino acid sequence data correlates with that predicted from the nucleotide sequence. The amino acid sequence around cleavage sites in the polyprotein shows no consistency, although a number of the virus-coded protease cleavage sites are between glutamate and glycine residues.

MeSH Terms
Amino Acid Sequence Aphthovirus/genetics Base Sequence Codon/genetics DNA Restriction Enzymes DNA, Recombinant/analysis Escherichia coli/genetics Genes, Viral Plasmids Protein Biosynthesis RNA, Viral/genetics Viral Proteins/genetics
Chemicals
Codon DNA, Recombinant RNA, Viral Viral Proteins DNA Restriction Enzymes
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Carroll A R
Rowlands D J
Clarke B E
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23 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/12.5.2461
Published
1984-03-12
Pages
2461-72
Language
English
Region
England
NLM ID
0411011
PMCID
PMC318676
Subset
IM
Databases
GENBANK
J02180, J02186, J02189, X00429
External Links
PubMed source DOI: 10.1093/nar/12.5.2461 PMC Full Text View journal details
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