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PMID: 6426 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Regulation of histidase synthesis in intergeneric hybrids of enteric bacteria.

Journal of bacteriology ·Vol. 127 ·No. 1 ·1976-07-00 ·Pages 114-9

Goldberg RB, Bloom FR, Magasanik B

Abstract

Regulation of the expression of the histidase coded by hutk of Klebsiella aerogenes in Salmonella typhimurium and in Escherichia coli and of the expression of the histidase coded by huts of S. typhimurium in E. coli was investigated. The hutk histidase was found to be sensitive to catabolite repression in K. aerogenes and in E. coli, but insensitive to catabolite repression in S. typhimurium; huts histidase has previously been shown to be catabolite sensitive in all three organisms. The expression of both hutk and huts histidase in E. coli was activated by nitrogen starvation. Apparently, the glutamine synthetase of E. coli may activate the formation of some glutamate- and ammonia-producing enzymes.

MeSH Terms
Ammonia-Lyases/biosynthesis Cell-Free System Enterobacter/enzymology,metabolism Enterobacteriaceae/enzymology Enzyme Repression Escherichia coli/enzymology,metabolism Galactosidases/metabolism Genes Glucose/metabolism Glutamate-Ammonia Ligase/metabolism Histidine Ammonia-Lyase/biosynthesis,metabolism Hybridization, Genetic Salmonella typhimurium/enzymology,metabolism Succinates/metabolism Tryptophanase/metabolism
Chemicals
Succinates Galactosidases Tryptophanase Ammonia-Lyases Histidine Ammonia-Lyase Glutamate-Ammonia Ligase Glucose
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Goldberg R B
Bloom F R
Magasanik B
References (22)
22 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.127.1.114-119.1976
Published
1976-07-00
Pages
114-9
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC233040
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.127.1.114-119.1976 PMC Full Text View journal details
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