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PMID: 6759877 Published · ppublish English Journal Article

Overlapping genes in the heat-labile enterotoxin operon originating from Escherichia coli human strain.

Molecular & general genetics : MGG ·Vol. 188 ·No. 2 ·1982-00-00 ·Pages 356-9

Yamamoto T, Tamura T, Yokota T, Takano T

Abstract

We have determined the nucleotide sequence at the distal end of the heat-labile enterotoxin subunit A (LT-A) gene (toxA) originating from human enterotoxigenic Escherichia coli. The sequenced region covers the entire LT-A2 region and a part of the LT-A1 region. In confirming our previous prediction based on product analysis of clones toxA regions, the data suggest the overlapping of the distal end (5'-TTA TGA) of toxA with the proximal end (5'-ATG AAT) of the LT subunit B gene (toxB), in the sequences 5'-TTATGAAT. Some additional characteristics of the LT operon as well as of the products are discussed.

MeSH Terms
Amino Acid Sequence Base Sequence Enterotoxins/genetics Escherichia coli/genetics Genes Genes, Bacterial Genetic Linkage Operon
Chemicals
Enterotoxins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Yamamoto T
Tamura T
Yokota T
Takano T
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23 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00332701
Published
1982-00-00
Pages
356-9
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
Databases
GENBANK
J01646
External Links
PubMed source DOI: 10.1007/BF00332701
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