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PMID: 6953406 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Beta subunits of human choriogonadotropin and ovine lutropin are biologically active.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 79 ·No. 8 ·1982-04-00 ·Pages 2500-3

Moudgal NR, Li CH

Abstract

Highly purified beta subunits of human choriogonadotropin and ovine lutropin were found to possess measurable steroidogenic activity in the in vitro rat Leydig cell assay. In addition, beta subunits of these two gonadotropins were able to inhibit the biological activity of human choriogonadotropin in the rat Leydig cell assay.

MeSH Terms
Animals Biological Assay Chorionic Gonadotropin/isolation & purification,pharmacology Humans Leydig Cells/drug effects,metabolism Luteinizing Hormone/isolation & purification,pharmacology Macromolecular Substances Male Rats Sheep Testosterone/biosynthesis
Chemicals
Chorionic Gonadotropin Macromolecular Substances Testosterone Luteinizing Hormone
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Moudgal N R
Li C H
References (18)
18 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.79.8.2500
Published
1982-04-00
Pages
2500-3
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC346226
Subset
IM
Grants
NIADDK NIH HHS · AM-6097 · United States
External Links
PubMed source DOI: 10.1073/pnas.79.8.2500 PMC Full Text View journal details
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