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PMID: 6968338 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Human homologue of murine T200 glycoprotein.

The Journal of experimental medicine ·Vol. 152 ·No. 4 ·1980-10-01 ·Pages 842-52

Omary MB, Trowbridge IS, Battifora HA

Abstract

We report the identification of the human homologue of murine T200 glycoprotein. Peptide-mapping experiments suggest that the structure of the glycoprotein is highly conserved between the two species. Many of the properties of human T200 homologue are similar to those of murine T200 glycoprotein: it is broadly distributed within the hematopoietic system but is not detectable on nonhematopoietic cells; there are also structural differences between the forms of the glycoprotein found on T and B lymphoblastoid cell lines. These results suggest the homologous glycoproteins may play similar functional roles in both species.

MeSH Terms
Antibody Formation Antigens, Surface/analysis Cell Line Glycoproteins/analysis Humans Leukemia, Lymphoid/analysis Methionine/analysis Species Specificity T-Lymphocytes/analysis
Chemicals
Antigens, Surface Glycoproteins Methionine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Omary M B
Trowbridge I S
Battifora H A
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Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.152.4.842
Published
1980-10-01
Pages
842-52
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2185975
Subset
IM
Grants
NCI NIH HHS · CA-20272 · United States
NCI NIH HHS · CA-21993 · United States
External Links
PubMed source DOI: 10.1084/jem.152.4.842 PMC Full Text View journal details
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