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PMID: 7969029 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Widespread occurrence of the Tc1 transposon family: Tc1-like transposons from teleost fish.

Molecular & general genetics : MGG ·Vol. 244 ·No. 6 ·1994-09-28 ·Pages 606-12

Radice AD, Bugaj B, Fitch DH, Emmons SW

Abstract

We characterized five transposable elements from fish: one from zebrafish (Brachydanio rerio), one from rainbow trout (Salmo gairdneri), and three from Atlantic salmon (Salmo salar). All are closely similar in structure to the Tc1 transposon of the nematode Caenorhabditis elegans. A comparison of 17 Tc1-like transposons from species representing three phyla (nematodes, arthropods, and chordates) showed that these elements make up a highly conserved transposon family. Most are close to 1.7 kb in length, have inverted terminal repeats, have conserved terminal nucleotides, and each contains a single gene encoding similar polypeptides. The phylogenetic relationships of the transposons were reconstructed from the amino acid sequences of the conceptual proteins and from DNA sequences. The elements are highly diverged and have evidently inhibited the genomes of these diverse species for a long time. To account for the data, it is not necessary to invoke recent horizontal transmission.

MeSH Terms
Amino Acid Sequence Animals Base Sequence DNA Transposable Elements/genetics Fishes/genetics Molecular Sequence Data Oncorhynchus mykiss/genetics Phylogeny Polymerase Chain Reaction Salmon/genetics Sequence Deletion Zebrafish/genetics
Chemicals
DNA Transposable Elements
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Radice A D
Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY 10461.
Bugaj B
Fitch D H
Emmons S W
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00282750
Published
1994-09-28
Pages
606-12
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
Grants
NIGMS NIH HHS · GM38174 · United States
Databases
GENBANK
L12206, L12207, L12208, L12209, L12210
External Links
PubMed source DOI: 10.1007/BF00282750
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