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PMID: 8039931 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected mice.

Infection and immunity ·Vol. 62 ·No. 8 ·1994-08-00 ·Pages 3568-71

Stevenson B, Bockenstedt LK, Barthold SW

Abstract

OspC from Borrelia burgdorferi reisolated from mice persistently infected with cloned spirochetes was examined. In all cases, the sequence of the ospC gene was identical to that of the original inoculant. We conclude that variation of ospC is not necessary for evasion of the host immune system.

MeSH Terms
Amino Acid Sequence Animals Bacterial Outer Membrane Proteins/analysis,genetics Base Sequence Borrelia burgdorferi Group/genetics,immunology Chronic Disease Female Lyme Disease/immunology,microbiology Male Mice Mice, Inbred C3H Molecular Sequence Data Polymerase Chain Reaction
Chemicals
Bacterial Outer Membrane Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Stevenson B
Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520.
Bockenstedt L K
Barthold S W
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.62.8.3568-3571.1994
Published
1994-08-00
Pages
3568-71
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC302995
Subset
IM
Grants
NIAID NIH HHS · AI26815 · United States
NIAID NIH HHS · AI30548 · United States
Databases
GENBANK
U04240
External Links
PubMed source DOI: 10.1128/iai.62.8.3568-3571.1994 PMC Full Text View journal details
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