Samples：40 Organism：Homo sapiens Type：transcription profiling by array Aug. 20, 2008

Gain-of-function mutations in NOTCH1 are common in T-cell lymphoblastic leukemias making this receptor a promising targe...

Samples：6 Organism：Mus musculus Type：transcription profiling by array June 15, 2008

Notch1 deficient hair matrix keratinocytes have lower mitotic rates, resulting in smaller follicles with fewer cells. In...

Samples：9 Organism：Mus musculus Type：transcription profiling by array June 15, 2008

Mutations in the Notch1 receptor and delta-like 3 (Dll3) ligand cause global disruptions in axial segmental patterning. ...

Samples：20 Organism：Homo sapiens Type：transcription profiling by array June 14, 2008

...NOTCH1. Here we show that NOTCH1 regulates PTEN expression and the activity of the PI3K-AKT signaling pathway in normal ...

Samples：28 Organism：Homo sapiens Type：transcription profiling by array June 14, 2008

...NOTCH1. Using an integrative systems biology approach we show that NOTCH1 controls a feed-forward loop transcriptional n...

Samples：4 Organism：Homo sapiens, Mus musculus Type：transcription profiling by array June 13, 2008

...Notch1 to restrict growth and promote differentiation. p63 functions as a selective modulator of Notch1-dependent transc...

Samples：4 Organism：Mus musculus Type：transcription profiling by array June 13, 2008

...Notch1, Socs1 and Id3) or the modulation of genes activating cell death through the ceramide pathway (Ugcg, Sgpp1, Degs1...

Samples：4 Organism：Mus musculus Type：transcription profiling by array June 11, 2008

...Notch1, c-Myc and cyclin E. We have generated conditional Fbw7 knock-out animals and inactivated the gene in hematopoiet...

Samples：4 Organism：Mus musculus Type：transcription profiling by array June 11, 2008

...Notch1 expression.

Samples：12 Organism：Mus musculus Type：unknown experiment type Sept. 14, 2007

Notch1 signaling is an important regulator of cell fate in early stages of T cell development. Because Notch receptors...