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Notch signaling activation in hPSC-derived CNS-like endothelial cells induces d…

Samples:10 Organism:Homo sapiens, Homo sapiens Type:RNA-seq of coding RNA Feb. 17, 2026

...Notch1 receptor intracellular domain (N1ICD). N1ICD overexpression in hPSC-CECs was induced by treatment with doxycyclin...

RNA-seq of wildtype and PIEZO1 knockout mice livers to investigate lipid and gl…

Samples:24 Organism:Mus musculus, Mus musculus Type:RNA-seq of coding RNA June 29, 2024

...Notch1 target genes in hepatic microvascular endothelium. Here, because of the liver’s dominant role in lipid regulation...

Extracellular Vesicles in acute coronary syndrome: carrier of epigenetics marks

Samples:13 Organism:Homo sapiens, Homo sapiens Type:Bisulfite-seq April 3, 2023

...NOTCH1, FOXO3, CDC42, IKBKG, RXRA, DGKG, known as important genes already involved in the onset of CVDs. Surprising, oth...

Genetic dynamics in untreated chronic lymphocytic leukemia patients with either…

Samples:52 Organism:Homo sapiens Type:genotyping by array Nov. 5, 2019

...NOTCH1, PIK3CA, POT1, SF3B1, TP53, XPO1 and ZMYM3, which were previously identified as mutated in CLL studies.

Deubiquitinase USP10 regulates Notch signaling in the endothelium

Samples:12 Organism:Homo sapiens Type:transcription profiling by array April 26, 2019

...NOTCH1 intracellular domain. HUVEC were transfected with scrambled or USP10 targeting siRNA and then stimulated by treat...

Quiescent endothelial cells upregulate fatty acid β-oxidation for vasculoprotec…

Samples:6 Organism:Mus musculus Type:RNA-seq of coding RNA Sept. 12, 2018

...Notch1 orchestrates the use of FAO for redox balance in QECs. Supplementation of acetate (metabolized to acetyl-CoA) ind...

Whole exome sequencing of TSCC (tongue squamous cell carcinoma)

Samples:24 Organism:Homo sapiens Type:DNA-seq May 31, 2018

...NOTCH1, CDKN2A, USP6, KMT2D etc, consistent with literature. We observed high frequency of CG/T(GC/A) transversions in n...

Whole Transcriptome sequencing TSCC (tongue squamous cell carcinoma)

Samples:15 Organism:Homo sapiens Type:RNA-seq of coding RNA May 31, 2018

...NOTCH1, CDKN2A, USP6, KMT2D etc, consistent with literature. We observed high frequency of CG/T(GC/A) transversions in n...

INTERLEUKIN 15-DEPENDENT T CELL-LIKE INNATE INTRAEPITHELIAL LYMPHOCYTES DEVELOP…

Samples:9 Organism:Homo sapiens Type:transcription profiling by array Nov. 23, 2016

...NOTCH1, interleukin 15 (IL-15) and Granzyme B signals. In NOTCH1-activated human hematopoietic precursors, IL-15 induced...

The transcriptional profile of human CD8+ lung resident memory T-cells

Samples:28 Organism:Homo sapiens Type:transcription profiling by array Oct. 23, 2016

...NOTCH1 and NOTCH2 receptors in T-cells, we demonstrated that Notch controls both the number of lung TRM as well as the f...

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