Samples：6 Organism：Mus musculus Type：transcription profiling by array Dec. 17, 2015

...RARA-activating retinoids in myeloid bone marrow cells and that that RARA remains in an un-liganded configuration during...

Samples：10 Organism：Homo sapiens Type：methylation profiling by array Nov. 8, 2012

...RARa knock-in mice did not show altered DNA methylation and expression of PML-RARa in hematopoietic progenitor cells pre...

Samples：8 Organism：Mus musculus Type：RNA-seq of coding RNA Oct. 21, 2016

...RARa. Total RNA extracted from Ring1b wild type and Ring1b KO Ring1a-/- Cdkn2a-/- Lin- HSC cells non-transduced or trans...

Samples：5 Organism：Homo sapiens Type：transcription profiling by array Nov. 4, 2014

A humanized in vivo APL model has been established utilizing the retroviral transduction of PML-RARA into human CD34+ he...

Samples：10 Organism：Mus musculus Type：ChIP-seq March 10, 2015

...RARa, sustains stable expression of Th1 lineage specifying genes as well as repressing genes that instruct Th17 cell fat...

Samples：12 Organism：Homo sapiens Type：transcription profiling by array Nov. 17, 2008

...RARa. The resulting PML-RARa is a transcriptional repressor that impedes the expression of RA-regulated genes notably th...

Samples：3 Organism：Homo sapiens Type：RNA-seq of coding RNA Feb. 17, 2016

...RARA fusion, other genetic alterations have also been implicated in APL. Here, we performed comprehensive mutational...

Samples：6 Organism：Homo sapiens Type：transcription profiling by array Dec. 14, 2009

...RARa fusion protein. Still, an important question that remains to be addressed is whether PML/RARa target genes are tran...

Samples：5 Organism：Homo sapiens Type：transcription profiling by array June 16, 2008

...RARA-PLZF status known were analysed for changes in expression related to the reciprocal status. This is a rare diseas...

Samples：11 Organism：Homo sapiens Type：transcription profiling by array April 25, 2009

...RARa antagonist (AGN193109) to block RARa mediated gene expression, or the RARa specific agonists (AM580) alone. This d...