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RARA fluorescence in situ hybridization overcomes the drawback of PML/RARA fluo…

Lee(DS),Lee(YS),Kim(YR),Han(KS),Park(KU),She… Cancer Genet Cytogenet 2002-12-00

...RARA FISH. A reference range for PML/RARA and RARA FISH was set using 50 normal control specimens. Using a RARA split pr...

Disulfide isomerase glucose-regulated protein 58 is required for the nuclear lo…

Zhu(L),Santos(NC),Kim(KH) Reproduction 2010-04-00

...RARA) is critical for spermatogenesis, as shown by a sterility phenotype observed in Rara knockout mice. RARA is importa...

A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4…

Duprez(E),Benoit(G),Flexor(M),Lillehaug(JR),… Leukemia 2000-02-00

...RARA and RARA transcription activity. These findings highlight the important role of the RARA E-domain of PML/RARA in me...

Rara haploinsufficiency modestly influences the phenotype of acute promyelocyti…

Welch(JS),Klco(JM),Varghese(N),Nagarajan(R),… Blood 2011-02-24

...RARA from the cathepsin G locus (mCG-PR). We found that Rara haploinsufficiency cooperated with PML-RARA, but only modes...

RNF8 is responsible for ATRA resistance in variant acute promyelocytic leukemia…

Yan(W),Li(J),Zhang(Y),Yin(Y),Cheng(Z),Wang(J… Cancer Cell Int 2019-00-00

...RARA-transfected HL60 cell model. We confirmed resistance of GTF2I-RARA to ATRA. Compared with PML-RARA, GTF2I-RARA has ...

PML-driven sumoylation of PML::RARA-bound repressors drives hematopoietic proge…

Wu(HC),Laplantine(E),Esnault(C),Niwa-Kawakit… J Exp Med 2026-09-07

...RARA-expressing, but not in RARA-expressing, progenitors and trigger APL differentiation. Thus, fusion of PML to RARA en...

The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic tr…

Boukarabila(H),Saurin(AJ),Batsché(E),Mossade… Genes Dev 2009-05-15

...RARA or PLZF/RARA is lost, whereas PRC1 recruited by PLZF/RARA remains, resulting in persistent RA-insensitive gene repr...

The novel ETV6::RARA fusion gene, identified in acute promyelocytic leukemia, i…

Hassani(MA),Huang(D),Gao(Y),Zhang(X),Tang(Z)… Ann Hematol 2026-03-14

...RARA t(12;17)(p13;q21), identified in an APL patient lacking the PML::RARA rearrangement. The ETV6-RARA fusion protein w...

Characterization of a rarely reported STAT5B/RARA gene fusion in a young adult …

Peterson(JF),He(RR),Nayer(H),Cuevo(RS),Smadb… Cancer Genet 2019-00-00

...RARA or variant RARA rearrangements is critical for the diagnosis and treatment of patients with newly diagnosed acute p...

In vitro response to all-trans retinoic acid of acute promyelocytic leukemias w…

Mozziconacci(MJ),Liberatore(C),Brunel(V),Gri… Genes Chromosomes Cancer 1998-07-00

...RARA and RARA/PML, and by its sensitivity to all-trans retinoic acid (ATRA) differentiating treatment. Rare APL cases la...

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