...RARA FISH. A reference range for PML/RARA and RARA FISH was set using 50 normal control specimens. Using a RARA split pr...
...RARA) is critical for spermatogenesis, as shown by a sterility phenotype observed in Rara knockout mice. RARA is importa...
...RARA and RARA transcription activity. These findings highlight the important role of the RARA E-domain of PML/RARA in me...
...RARA from the cathepsin G locus (mCG-PR). We found that Rara haploinsufficiency cooperated with PML-RARA, but only modes...
...RARA-transfected HL60 cell model. We confirmed resistance of GTF2I-RARA to ATRA. Compared with PML-RARA, GTF2I-RARA has ...
...RARA-expressing, but not in RARA-expressing, progenitors and trigger APL differentiation. Thus, fusion of PML to RARA en...
...RARA or PLZF/RARA is lost, whereas PRC1 recruited by PLZF/RARA remains, resulting in persistent RA-insensitive gene repr...
...RARA t(12;17)(p13;q21), identified in an APL patient lacking the PML::RARA rearrangement. The ETV6-RARA fusion protein w...
...RARA or variant RARA rearrangements is critical for the diagnosis and treatment of patients with newly diagnosed acute p...
...RARA and RARA/PML, and by its sensitivity to all-trans retinoic acid (ATRA) differentiating treatment. Rare APL cases la...
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