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Somatic mutations in lymphocytes in patients with immune-mediated aplastic an...

样本量:6 物种:Homo sapiens, Homo sapiens 类型:Human - Single-cell sequencing, RNA-s... 2021年3月24日

...KRAS and other mutations in CD8+ T cells. The analysis was performed using V(D)J and 5' gene expression platform (10X Ge...

Expression profile of A459 cells upon LKB1 expression

样本量:6 物种:Homo sapiens, Homo sapiens 类型:Cell line - One-color microarray, tra... 2020年6月11日

...KRAS mutated and null for STK11. Cells were previously infected with the lentiviral construct pLenti-rtTA2-IRES-H2B-GFP ...

Transcriptomic output of endogenous KRasG12D and modestly overexpressed MYC i...

样本量:12 物种:Mus musculus, Mus musculus 类型:RNA-seq of coding RNA 2020年3月16日

...KRasG12D (LSL-KRasG12D) and MYC (Rosa26-LSL-MYC), alongside double positive and wild-type control MEFs. All MEFs were i...

RNA-SEQ analysis of pancreatic ductal adenocarcinoma tumours in Pdx1-Cre;lsl-...

样本量:21 物种:Mus musculus, Mus musculus 类型:Animal - High-throughput sequencing, ... 2020年3月16日

Activation of endogenously expressed KRas[G12D] in the pancreas of mice gives rise primarily to early stage PanIN lesion...

RNA-SEQ analysis of KMC murine pancreatic ductal adenocarcinoma (PDAC) cell l...

样本量:16 物种:Mus musculus, Mus musculus 类型:Cell line - High-throughput sequencin... 2020年3月16日

...KRAS or to act as a downstream KRAS effector - here we compared the transcriptomic impact of MYC depletion with that of ...

RNAseq of pancreata from KRasG12D/RosaMycER treated with Tamoxifen for differ...

样本量:12 物种:Mus musculus 类型:RNA-seq of coding RNA 2020年1月6日

...KRasG12D/RosaMycER mouse model KRas and MycER are expressed exclusively in the pancreas, but MycER activity depends on T...

Genetic dynamics in untreated chronic lymphocytic leukemia patients with eith...

样本量:52 物种:Homo sapiens 类型:genotyping by array 2019年11月5日

...KRAS, MED12, NRAS, RIPK1, SAMHD1, ATM, BIRC3, BRAF, CHD2, DDX3X, DDX3Y, FBXW7, KIT, KLHL6, MAPK1, MYD88, NOTCH1, PIK3CA,...

Genomic characterization of intrinsic and acquired resistance to cetuximab in...

样本量:31 物种:Homo sapiens 类型:genotyping by array 2019年9月21日

...KRAS K117N and A146T mutations in addition to BRAF V600E, AKT1 E17K, PIK3CA E542K, and FGFR1 or ERBB2 amplifications. Th...

Whole exome sequencing of human tumours and cell lines to investigate how ERB...

样本量:22 物种:Homo sapiens 类型:DNA-seq 2018年12月29日

...KRAS (G13D) but not KRAS (G12V) mutation. Furthermore, we show in vivo reduction in tumor size is paralleled by a reduct...

RNA-seq to investigate impact of treatment of KRAS mutant A549 lung adenocarc...

样本量:6 物种:Homo sapiens 类型:RNA-seq of coding RNA 2018年6月1日

KRAS mutation is widely presumed to confer independence from upstream RTK signalling, however emerging evidence from mou...

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