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Multiomics of three distinct hematological malignancies in a patient reveals ...

样本量:39 物种:Homo sapiens, Homo sapiens 类型:spatial transcriptomics by high-throu... 2023年3月17日

...LYN deleterious mutations, DLBCL-NOS disclosed KRAS, STAT6, CREBBP and ATM alterations and AML-M5 had JAK3, PPM1D, NF1 a...

RNA-Seq analysis of LYN deficient HS-5 stroma cells cocultured with primary h...

样本量:12 物种:Homo sapiens 类型:RNA-seq of coding RNA 2023年2月10日

LYN kinase is a tyrosine kinase, that regulates cellular homeostasis in a context-specific manner. Our group could show,...

RNA-Seq analysis of LYN deficient stromal cells sorted from murine spleens

样本量:7 物种:Mus musculus 类型:RNA-seq of coding RNA 2023年2月10日

...LYN deficiency on murine splenic stromal cells by FACS-sorting stroma cells from Lyn(wt/wt) and Lyn(-/-) spleen (7AAD-C...

Transcriptome of LYN deficient HS-5 stroma cells

样本量:4 物种:Homo sapiens, Homo sapiens 类型:transcription profiling by array 2023年1月1日

LYN kinase is a tyrosine kinase, that regulates cellular homeostasis in a context-specific manner. Our group could show,...

Gene expression profiling in wild-type, Irf5-KO, Lyn-KO and Lyn/Irf5-DKO BMDC...

样本量:24 物种:Mus musculus 类型:transcription profiling by array 2016年7月25日

...Lyn particularly suppresses IRF5 induction of type I IFNs. BMDCs from WT, Irf5-KO, Lyn-KO and Lyn/Irf5-DKO mice in a C57...

Identification of novel androgen-regulated pathways and mRNA isoforms through...

样本量:32 物种:Homo sapiens 类型:transcription profiling by array 2011年12月27日

...LYN, as well as components of the mTOR (mammalian target of rapamycin) pathway, which is commonly dysregulated in cancer...

Epstein Barr virus Nuclear Antigen 3C regulated genes in Lymphoblastoid Cell ...

样本量:33 物种:Homo sapiens 类型:transcription profiling by array 2011年1月6日

...LYN and TNF upstream of other EBNA3C regulated genes. Further, Gene Set Enrichment Assay (GSEA) identified EBNA3C regula...

Adult T-cell leukemia-lymphoma and AZT-IFNa combination therapy

样本量:36 物种:Homo sapiens 类型:transcription profiling by array 2010年4月12日

...LYN, CSPG2 and LMO2, with confirmation of LMO2 expression confirmed in ATLL cells at the protein level. In vivo AZT- and...

Prognostic signature of epithelial-mesenchymal transition in breast cancer

样本量:40 物种:Homo sapiens 类型:transcription profiling by array 2010年4月11日

...LYN kinase activity, suggesting that LYN is a likely target and invasion a relevant endpoint for dasatinib therapy. Our...

Transcription profiling of human pancreatic cancer treated with masitinib com...

样本量:4 物种:Homo sapiens 类型:transcription profiling by array 2009年9月17日

...Lyn of the Src kinase family. We evaluated the therapeutic potential of masitinib in vitro on human pancreatic tumour ce...

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