...LYN-1604 restores sunitinib sensitivity in PDZK1-knockdown cells and synergizes with sunitinib in xenograft models, redu...
...Lyn kinase; Lyn was increasing the threshold for TRPV4 responsiveness to LPS. To translate these findings to an in vivo ...
...Lyn kinase activation and suppressed SP-and Tween 80-induced β-hexosaminidase release, exhibiting an inhibitory profile ...
...LYN, and TEC as potential upstream kinases of CAV1_Y14, whereas CSNK1E and GRK5 were predicted to regulate CAV1_S37. Con...
...LYN are important for EVT development. Our findings highlight key kinases uniquely required for specific stages of troph...
Engineered mutant AireGW/+Lyn-/- C57BL/6 mice are a model of spontaneous autoimmunity in which 50% of mice develop highl...
...LYN-1604 or inhibitor MRT68921 at EC₅₀ concentrations. Autophagic activity, validated through LC3B immunoblotting and fl...
...Lyn, Syk and ERK. Knockout of Treml4 significantly reversed the phosphorylation of Lyn, Syk, and ERK in the hippocampus,...
...Lyn, and Fcgr1, providing new insight into PU.1-dependent regulatory networks and microglial functions in neurodegenerat...
...LYN, FLT1, and KDR. Survival analysis identified LYN, FLT3, and PDGFRA as prognostic biomarkers (p < 0.05). Molecular do...
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