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Expression and alternative splicing of folate pathway genes in HapMap lymphobla…

Duan(Shiwei),Huang(R Stephanie),Zhang(Wei),M… Pharmacogenomics 2009-07-31

...FPGS and the splicing indices of eight genes (ATP13A2, ASCC3L1, IFIH1, SMARCA5, SMARCA2, SETX, DDX52 and RUVBL2) were fo...

Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthr…

Sharma(Shruti),Das(Mitashree),Kumar(Ashok),M… Pharmacogenet Genomics 2009-12-23

...FPGS rs1544105, TYMS rs2853539, DHFR rs7387, and ADA rs244076 were identified as putative predictors for MTX response. C...

Identification and validation of suitable endogenous reference genes for gene e…

Stamova(Boryana S),Apperson(Michelle),Walker… BMC Med Genomics 2009-12-14

...FPGS, FARP1, MAPRE2, PEX16, GINS2, CRY2, CSNK1G2 and A4GALT), 4 commonly employed reference genes (GAPDH, ACTB, B2M and ...

p16INK4a gene promoter hypermethylation in mucosa as a prognostic factor for pa…

Wettergren(Yvonne),Odin(Elisabeth),Nilsson(S… Mol Med 2008-09-30

Low gene expression of folylpolyglutamate synthase (FPGS) in colorectal mucosa correlates with low folate levels and poo...

Asymmetric synthesis of inhibitors of glycinamide ribonucleotide transformylase.

DeMartino(Jessica K),Hwang(Inkyu),Connelly(S… J Med Chem 2008-10-24

...FPGS) but not intracellular transport by the reduced folate carrier.

Recent advances in classical and non-classical antifolates as antitumor and ant…

Gangjee(Aleem),Jain(Hiteshkumar D),Kurup(Son… Anticancer Agents Med Chem 2008-04-03

...FPGS). Recently, classical antifolates that do not need to be polyglutamylated have also been developed and include plev...

Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity…

Ranganathan(Prabha),Culverhouse(Robert),Mars… J Rheumatol 2008-07-15

...FPGS), methylenetetrahydrofolate reductase (MTHFR), and thymidylate synthase (TYMS). Both cohorts included Caucasian Ame...

Evaluation of the FocalPoint GS system performance in an Italian population-bas…

Passamonti(Basilio),Bulletti(Simonetta),Cami… Acta Cytol 2008-01-03

To evaluate the FocalPoint Location-Guided Screening (FPGS) performance in computer-assisted primary screening of Papani...

Colorectal carcinomas with microsatellite instability display increased thymidy…

Odin(Elisabeth),Wettergren(Yvonne),Nilsson(S… Clin Colorectal Cancer 2008-04-29

...FPGS), and methylenetetrahydrofolate reductase (MTHFR) in mucosa and tumor were compared with patients with MSS. Further...

Concentration-dependent processivity of multiple glutamate ligations catalyzed …

Tomsho(John W),Moran(Richard G),Coward(James… Biochemistry 2008-09-09

Folylpoly-gamma-glutamate synthetase (FPGS, EC 6.3.2.17) is an ATP-dependent ligase that catalyzes formation of poly-gam...

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