...RARA fusions in APL-like cases lacking PML::RARA. TTMV::RARA APL may be sensitive to ATRA/ATO-based therapy; however, th...
...RARA, NUMA-RARA, FIP1L1-RARA, IRF2BP2-RARA, and TFG-RARA have been demonstrated to be sensitive to ATRA, so combined che...
...rara and lamina densa. Our results indicate that the lamina rara is not a fixation artifact and it has common antigenic ...
...RARA fusion message. Separate PCR assays were designed to amplify either PML-RARA (15q+ derived) or RARA-PML (17q- deriv...
...RARA status. MIR125B1 overexpression enhanced PML-RARA expression and inhibited the ATRA-induced degradation of the PML-...
...RARA-APL and subsequent administration of two rounds of ATRA-based treatment, the patient rapidly developed multiple RAR...
...RARA transcripts was analyzed by a highly sensitive PCR assay. Despite gene proximity, typical PML-RARA transcripts were...
...RARA fusion transcripts derived from a combination of NPM1 exon 4 and RARA exon 5, or of NPM1 exon 1 and RARA exon 5; th...
Acute promyelocytic leukemia (APL) is driven by the specific fusion gene PML-RARA produced by chromosomal translocation....
...RARA mutant exhibit defective As(2)O(3) response. Conversely, nonarsenical oxidants elicit PML/RARA multimerization, NB-...
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