Leil(Tarek A),Endo(Chiaki),Adjei(Araba A),Dy… Cancer Res 2007-11-27

...FPGS gene, FPGS, have resequenced the gene in four different ethnic populations. Thirty-four single nucleotide polymorph...

Dotzlaf(Joe),Carpenter(John),Luo(Shuang),Mil… Hybridoma (Larchmt) 2007-08-20

...FPGS by these MAbs should provide useful reagents for FPGS quantitation in either tumor cell lysates or in tumor biopsie...

Gangjee(Aleem),Jain(Hiteshkumar D),Kurup(Son… Anticancer Agents Med Chem 2007-11-02

...FPGS). Novel antifolates have been developed that do not need to be polyglutamylated and include plevitrexed (6) and GW1...

Hanauske(Axel-Rainer),Eismann(Ulrike),Obersc… Invest New Drugs 2007-11-05

...FPGS), thymidylate synthase (TS), dihydrofolate reductase (DHFR), glycinamide ribonucleotide formyl transferase (GARFT),...

Du(Zhi-You),Chen(Fei-Fei),Liao(Qian-Sheng),Z… J Gen Virol 2007-09-26

...FPGs(2b)-CMV, FRad35(2b)-CMV and FNa(2b)-CMV, respectively. FCb7(2b)-CMV was more virulent than Fny-CMV, and was similar...

van der Straaten(R J H M),Wessels(Judith A M… Pharmacogenomics 2007-11-30

...FPGS 114G>A, causing an amino acid change with no known frequencies. In this study, frequencies of two SNPs in FPGS (199...

Lim(Unhee),Wang(Sophia S),Hartge(Patricia),C… Blood 2007-05-31

...FPGS Ex15-263T>C, and SHMT1 Ex12+138C>T and Ex12+236C>T. Furthermore, significant gene-nutrient interactions limited the...

Gangjee(Aleem),Yang(Jie),McGuire(John J),Kis… Bioorg Med Chem 2007-02-02

...FPGS), the enzyme responsible for forming critical poly-gamma-glutamate antifolate metabolites with increased potency an...

Leclerc(Guy J),York(Teresa A),Hsieh-Kinser(T… Leuk Res 2007-11-01

...FPGS and SLC19A1 mRNA expression, examined FPGS promoter activity, and determined nucleotide sequence of the FPGS promot...

Assaraf(Yehuda G) Cancer Metastasis Rev 2007-06-13

...FPGS). As the intracellular concentration of antifolates is critical for their pharmacologic activity, polyglutamylation...