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What is new on the horizon for the biologics world: New kids of the block - WAO…

Canonica(GW),Ortega-Martell(JA),Villarreal-G… World Allergy Organ J 2026-03-00

...SYK, and STAT6 degraders, show promise as oral alternatives to injectable therapies. Clinical trials report high efficac...

Precision Glyco-Modulated GcMAF2.0 Targets CLEC10A to Bidirectionally Re-Wire M…

Pokushalov(E),Kudlay(D),Bogachev(S),Johnson(… Immunology 2026-08-00

...SYK versus STAT6/PPARγ cascades and shifts in arginine, glucose and fatty-acid metabolism. Cross-species data from roden...

Glycogen phosphorylase L confers metabolic flexibility in neutrophils to fight …

Choi(W),Li(DD),McLaughlin(CT),Peroumal(D),Sh… Cell Host Microbe 2026-04-08

...Syk and protein kinase A (PKA) kinases drive glycogenolysis in neutrophils. Neutrophil-specific deletion of PYGL in mice...

Lindblad many-body scars.

García-García(AM),Lu(Z),Sá(L),Verbaarschot(J… Phys Rev E 2026-02-00

...SYK) model with N fermions, either Majorana or complex, we construct analytically some of these Lindblad scars while oth...

Characterization of acetovanillone degradation in wild-type and engineered Rhod…

Lalande(AT),Wolf(ME),Robeck(LD),Eltis(LD) Appl Environ Microbiol 2026-04-22

...SYK-6, respectively. All three pathways preferentially converted AV and HAP over AS. However, the strain expressing the ...

The B cell receptor-mTOR signaling axis restricts the accumulation of lung tiss…

Anupam(K),Patel(K),Andhare(P),Henry(B),Hanso… Sci Immunol 2026-03-20

...SYK downstream of the BCR restricted lung BRM cell accumulation. Conversely, inhibition of mTOR using rapamycin reduced ...

Identification of ursolic acid from Wumei as a syk-targeting anti-allergic agen…

Xu(Z),Miao(B),Gu(Z),Hu(Y),Tang(D),Li(J) J Pharm Biomed Anal 2026-08-15

...Syk was demonstrated by the elevated thermostability of ursolic acid-Syk complex. Molecular docking and molecular dynami...

Aβ-Overlapping Ectodomain Binding of the Clinical-Stage TREM2 Agonist VG-3927.

Cho(S),Gabr(MT) bioRxiv 2026-03-05

...SYK signaling. Together, these findings support the presence of a previously unrecognized ectodomain interaction mode fo...

Peptidoglycan recognition proteins in the brain: Role in neuroinflammation and …

Suk(K),Lee(WH) Histol Histopathol 2026-03-18

...Syk-Erk1/2-Stat3 signaling axis, establishing a positive feedback loop with TNF-α that perpetuates microglial activation...

Platform Potential of Sphingobium lignivorans SYK-6 for Lignin Valorization via…

Kamimura(N),Endo(M),Nakamura(B),Akiyama(T),K… J Agric Food Chem 2026-04-01

...SYK-6 to funnel aromatic mixtures in black liquor from oxygen-soda-anthraquinone pulping into the polymer building block...

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