Kimme(P),Ledin(T),Sjöberg(F) Acta Physiol Scand 2003-03-06

...FPGs were found only when all values sampled were clustered together, whereas, as a new finding, data are presented indi...

Gangjee(Aleem),Dubash(Nauzer P),Zeng(Yibin),… Curr Med Chem Anticancer Agen… 2003-04-22

...FPGS. FPGS activity on natural folate is essential to cell proliferation and survival. Thus inhibition of FPGS activity ...

Wang(Yanhua),Zhao(Rongboa),Goldman(I David) Biochem Pharmacol 2003-05-01

...FPGS) message was decreased by 65% in MTA-13 cells. No mutations were detected in either protein by DNA sequence analysi...

McGuire(John J),Haile(William H),Valiaeva(Na… Biochem Pharmacol 2003-02-13

...FPGS. Within experimental limits, FPGS inhibition was not time-dependent, and preincubation of FPGS, inhibitor, and ATP ...

Sheng(Yi),Ip(Hermia),Liu(Jun),Davidson(Alan)… Biochemistry 2003-05-02

...FPGS) catalyzes the addition of glutamate to folate derivatives to form folate polyglutamates. FPGS is essential for fol...

Gangjee(Aleem),Yu(Jianming),Kisliuk(Roy L),H… J Med Chem 2003-03-10

...FPGS), 4 was a poor substrate of FPGS. Compound 2 showed GI50 values in the nanomolar range against more than 18 human t...

Tsukamoto(Takashi),Flanary(Juliet M),Rojas(C… Bioorg Med Chem Lett 2003-05-16

...FPGS) and gamma-glutamyl hydrolase (gamma-GH) provides insight into structural and mechanistic features of each enzyme. ...

Sigmond(Jennifer),Backus(Harold H J),Wouters… Biochem Pharmacol 2003-09-12

...FPGS) and reduced folate carrier (RFC). WiDr-4PEM and WiDr-cPEM showed cross-resistance to the polyglutamatable TS inhib...

Marsilje(Thomas H),Labroli(Marc A),Hedrick(M… Bioorg Med Chem 2003-07-31

...FPGS(-)) establishing that their potent activity requires both reduced folate carrier transport and polyglutamation. Une...

Stranzl(T),Wolf(J),Leeb(B F),Smolen(J S),Pir… Clin Exp Rheumatol 2003-06-17

...FPGS mRNA. FPGS mRNA expression was not associated with age, sex, disease duration, white blood cell count, erythrocyte ...