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TP53 BRCA1 CRISPR single-cell cancer

Borrow(J),Shipley(J),Howe(K),Kiely(F),Goddar… Genes Chromosomes Cancer 1994-04-00

...RARA) gene on chromosome 17. A PML-RARA fusion message transcribed from the der(15) is thought to mediate leukemogenesis...

Wells(RA),Catzavelos(C),Kamel-Reid(S) Nat Genet 1997-09-00

...RARA. In more than 99% of cases, this disruption results in the formation of a PML-RARA gene fusion. Two rare variants o...

Chen(Z),Chen(SJ) Leuk Lymphoma 1992-11-00

...RARA fusion gene and to detect minimal residual disease (MRD). The biological activity of the PML-RARA fusion gene and i...

Yin(CC),Jain(N),Mehrotra(M),Zhagn(J),Protopo… J Natl Compr Canc Netw 2015-01-00

Acute promyelocytic leukemia (APL) is characterized by the fusion of retinoic acid receptor alpha (RARA) with promyelocy...

Chakraborty(S),Wang(S),Ruhala(J),Mehling(B),… Proc Natl Acad Sci U S A 2025-07-00

...RARA) has a dual role in cochlear organogenesis: First, during embryonic development, in the presence of RA, RARA functi...

Zha(X),Wu(G),Zhang(H),Yang(Y),Zhang(Y),Ma(L) Anim Cells Syst (Seoul) 2019-00-00

...RARA in ARPE-19 cells, and H2O2 and blue light could significantly reduce the RARA protein expression, and also could in...

Welch(JS),Yuan(W),Ley(TJ) J Clin Invest 2011-04-00

...RARA) in nearly all cases. Multiple prior mouse models of APL constitutively express PML-RARA from a variety of non-Pml ...

Ma(L),Wu(M) Ann Hematol 2026-05-12

None

Zaccaria(A),Valenti(A),Toschi(M),Salvucci(M)… Cancer Genet Cytogenet 2002-10-15

Cryptic translocations in acute promyelocytic leukemia are rare. Usually the gene fusion PML/RARA is located on chromoso...

Fujishima(M),Takahashi(N),Miura(I),Kobayashi… Cancer Genet Cytogenet 2000-07-01

...RARA dual color DNA probe. FISH showed a PML/RARA fusion gene on the der(2) instead of the der(15). These results sugges...

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