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Classificação das doenças neurometabólicas hereditárias baseada em aspectos rad…

Pedri(AF),Guedes(MDS),de Castro(CC) Radiol Bras 2022-00-00

...raras, mas atingem pelo menos um a cada mil nascimentos. Algumas têm possibilidade terapêutica. Os quadros clínico e rad...

Dysregulation of the ALDH1A3/PML-RARα axis promotes the progression of acute pr…

Cai(J),Liang(CH),Han(LP),Jiang(HY),Duan(JJ),… Cancer Lett 2026-04-01

...RARA fusion gene, plays a central role in the pathogenesis of acute promyelocytic leukemia (APL). The activation of this...

DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic…

Pan(S),Lai(H),Shen(Y),Breeze(C),Beck(S),Hong… Cardiovasc Res 2017-05-01

...RARA in AD, a pattern which is also seen in cells exposed to smoke toxins. Our data supports a model in which increased ...

Dismal outcome of therapy-related myeloid neoplasm associated with complex aber…

Tang(YL),Chia(WK),Yap(EC),Julia(MI),Leong(CF… Malays J Pathol 2016-12-00

...RARA gene was negative. Karyotyping result revealed complex abnormalities and monosomal karyotype (MK). A diagnosis of t...

Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.

Kramer(MH),Zhang(Q),Sprung(R),Day(RB),Erdman… Blood 2022-00-29

...RARA-initiated AML samples displayed a unique phosphorylation signature, and TP53-mutant samples showed abundant phospho...

BRD4 PROTAC degrader MZ1 exerts anticancer effects in acute myeloid leukemia by…

Ma(L),Wang(J),Zhang(Y),Fang(F),Ling(J),Chu(X… Cancer Biol Ther 2022-00-31

...RARa), K562 (BCR-ABL), Kasumi-1 (AML1-ETO), and MV4-11 (MLL-AF4) cell lines representing different molecular subtypes of...

The role of adjuvant chemotherapy in the management of acute promyelocytic leuk…

LaBella(D),Regan(S),Konig(H),Egan(DN),Bailey… Front Oncol 2022-00-00

...RARA fusion protein. The all-trans-retinoic acid (ATRA) and Arsenic Trioxide (ATO) only regimens have demonstrated succe...

Development of a NanoString assay to detect leukemogenic fusion transcripts in …

Hu(D),Zhou(W),Wang(F),Shu(SM),Fan(LL),He(J),… Int J Lab Hematol 2016-12-00

...RARA (bcr1, bcr2, and bcr3), and CBFB-MYH11 (e5e12, e5e8, and e5e7). We set up the cut-off value for each fusion transcr...

Rapid detection of myeloid neoplasm fusions using single-molecule long-read seq…

Sala-Torra(O),Reddy(S),Hung(LH),Beppu(L),Wu(… PLOS Glob Public Health 2023-00-00

...RARA, CBFB::MYH11, KMT2A::AFF1) using cloud-based bioinformatics workflows with novel custom fusion finder software. We ...

Influence of maternal or neonatal Vitamin A injection on calf performance and m…

Oliveira(JM),Casagrande(DR),Laura(SAS),Horta… Trop Anim Health Prod 2026-03-14

...RARA, MYF5, CEBPA, and DLK1 were higher (P ≤ 0.05) expressed in Control and VAcow calves than in VAcalf calves. Expressi...

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