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Characterisation of genome-wide PLZF/RARA target genes.

Spicuglia(S),Vincent-Fabert(C),Benoukraf(T),… PLoS One 2011-00-00

...RARA-dependent leukaemogenesis still remain unclear.We searched for specific PLZF/RARA target genes by ChIP-on-chip in t...

Characterization of cryptic rearrangements, deletion, complex variants of PML, …

Amare(PK),Baisane(C),Nair(R),Menon(H),Banava… Indian J Hum Genet 2011-05-00

...RARA and/or RARA variants. D-FISH with PML/RARA probe helped identification of RARA insertion to PML. By application of ...

The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/R…

Yang(WC),Shih(HM) Oncogene 2013-10-24

...RARA protein half-life, correlating with down- or upregulation of PLZF/RARA poly-ubiquitination, respectively. By PLZF/R...

Report of IRF2BP1 as a novel partner of RARA in variant acute promyelocytic leu…

Jiang(M),Wang(X),Yu(M),Jiang(S),Hong(M),Zhou… Am J Hematol 2024-00-00

...RARA breakpoint and acceptor AG at the 5' end of RARA exon 3. The IRF2BP1::RARA fusion gene leads a fusion transcript in...

Identification of concurrent STAT3::RARA and RARA::STAT5b fusions in a variant …

Tao(T),Cen(J),Xu(C),Chen(Y),Cao(Y),Gong(Y),Z… Mol Carcinog 2024-04-00

...RARA fusion cannot be detected. In this report, we identified the coexistence of STAT3::RARA and RARA::STAT5b fusions fo...

Clinical significance of increased PML-RARa transcripts after induction therapy…

Liang(M),Wang(L),Xiao(M),Xiong(J),Wang(J),Wa… Ann Med 2020-00-00

...RARa transcripts increased after induction therapy.Methods: We analyzed 9 cases of APL whose PML-RARa transcripts increa...

Atypical mRNA fusions in PML-RARA positive, RARA-PML negative acute promyelocyt…

Walz(C),Grimwade(D),Saussele(S),Lengfelder(E… Genes Chromosomes Cancer 2010-05-00

...RARA forward DNA fusion and expressed a chimeric PML-CDC6-RARA mRNA in addition to a PML-RARA. The other two had HERC1-P...

Retinoic Acid Receptor Alpha Is Essential in Postnatal Sertoli Cells but Not in…

Condrea(D),Souali-Crespo(S),Féret(B),Klopfen… Cells 2022-00-04

...RARA) induces male sterility due to seminiferous epithelium degeneration. Initial genetic studies established that RARA ...

A novel RARA-SNX15 fusion in PML-RARA-positive acute promyelocytic leukemia wit…

Hirade(K),Kusumoto(S),Abe(A),Noritake(H),Ito… Int J Hematol 2022-12-00

...RARA-PML is present in over 80% of t(15;17) APL cases. The bcr3 types of RARA-PML and RARA-PLZF in particular are recipr...

PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self…

Katerndahl(CDS),Rogers(ORS),Day(RB),Xu(Z),He… Proc Natl Acad Sci U S A 2024-04-30

...RARA in primary mouse and human hematopoietic progenitor cells with V5-tagged PML::RARA, using anti-V5-PML::RARA chromat...

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