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Unconventional role of hydroxymethylglutaryl-CoA synthase 1 in driving pathogen…

Sun(J),Lei(Y),Yang(H),Li(S),Wu(B) Sci Adv 2026-08-21

...Rorc). Mechanistically, HMGCS1 is located to the ER membrane, where it bound and stabilized IRE1α protein. This stabiliz...

Human inherited RORγT deficiency encompasses genetic heterogeneity, T cell defi…

Fagniez(I),Tsumura(M),Guerin(A),Abolhassani(… medRxiv 2026-07-20

...RORC variant. All but one patient - the exception receiving early prophylaxis - developed mycobacterial disease due to a...

Dysregulation of T Helper 17 Cell Pathway In Vitiligo.

Venkatesh(V),Mendez(D),Srinivas(RT),Balakris… Indian J Dermatol None

...RORC gene expression for the mediator component, and plasma IL17A for the effector component. The study was carried out ...

RORγt+ dendritic cells are a distinct lymphoid-derived lineage.

Rodrigues(PF),Wu(S),Trsan(T),Bhattarai(B),Pa… Sci Immunol 2026-02-20

...Rorc(t)+ progenitors, which include a RORγt+ innate lymphoid progenitor (RILP) that generates both ILC3s and RORγt+ DCs,...

A facile synthesis of [1,2,3]triazolo[1,5-a]quinazolines via a copper-catalyzed…

Liu(X),Wang(H),Liu(Y),Wang(C),Liu(C),Chen(Y) Org Biomol Chem 2026-01-14

...RORC) process of Dimroth rearrangement probably was driven by thermodynamic stability.

Endometrial molecular genetic phenotypes and histological endometrial phase in …

Alanazi(HA),Ganieva(U),Thees(A),Fatunbi(J),L… J Reprod Immunol 2026-02-00

...RORC, and higher expression of HOXA10 genes, than in-phase samples. These findings suggest that molecular genetic evalua...

Conjunctival allergic inflammation involving the interleukin-23/T helper type 1…

Adachi(R),Shoji(J),Inada(N),Tomioka(A),Yamag… Jpn J Ophthalmol 2026-07-00

...Rorc and Il1r1 expression in the IL-23 group. At the same time, Mmp3, Ccl7, and Ccr2 were significantly upregulated in t...

Dehydrocorydaline treatment suppresses Th17 differentiation via the mTOR-mediat…

Liu(J),Zheng(J),Sun(Y),Li(W),Fu(H),Zeng(J),W… Mol Med 2026-02-13

...Rorc transcription during Th17 polarization. CONCLUSION: DHC attenuates renal damage in SLE by suppressing the Th17 resp...

LINGO4 coordinates ILC3-intrinsic IL-22 production and microbiota-mediated ILC3…

Fachi(JL),Trsan(T),Sécca(C),de Oliveira(S),R… J Exp Med 2026-06-01

...Rorc, the gene for RORγt, raising the possibility that it contributes to the biology of RORγt+ lymphocytes. However, its...

Therapeutically targetable Th17-derived miR-721 drives autoimmune myocarditis t…

Ruiz-Fernández(I),Sánchez-Díaz(R),Blanco-Dom… bioRxiv 2026-03-26

...Rorc double inhibitory axis. Hsa-RNA-Chr8:96 targets human PPARG mRNA for degradation, inhibiting its expression Blockad...

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