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RORC

Gene name:RAR related orphan receptor C

...RORC基因编码两种异构体:RORγ和RORγt,其中RORγt是胸腺细胞和某些免疫细胞(如Th17细胞、ILC3细胞)的特异性亚型,对免疫系统功能至关重要。RORC的生物学功能包括促进Th17细胞分化(分泌IL-17等促炎细胞因子)、调节...

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