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Single-cell omics and flow cytometry identify distinct immune states of dural a…

Zha(M),Jander(A),Cai(H),Piepke(M),Degenhardt… J Neuroinflammation 2026-04-09

...Rorc⁺ and belonged to the Vγ6⁺ γδ17 cell subset. Compared to dural γδ T cells, brain-infiltrating γδ T cells showed redu...

Identification and Validation of RORC as a Circadian Rhythm-Related Biomarker i…

Liu(X),Ren(B),Ma(W),Fu(L),Liu(S),Sun(D) Int J Gen Med None

...RORC in GC cells were investigated through CCK8, colony formation, and Transwell assays. RORC has been identified as a p...

Enhanced HIF-1α cooperation by a human RORγt mutant potentiates Th17 pathogenic…

Dong(P),Liu(L),Yu(J),Li(N),Davidorf(B),Shen(… Cell Rep 2026-03-17

...RORC variants to inflammatory diseases, their functional consequences remain poorly understood. We identify a pathogenic...

METTL3-targeted intervention on nuclear factors RORA/RORγt suppresses pathogeni…

Xia(X),Long(C),Chen(W),Yao(X),Xu(B),Teng(H),… Kidney Int 2026-06-00

...RORC) expression through elevating Smad2 and STAT3 phosphorylation levels in an m6A-independent manner. Furthermore, spe...

RORγt+ APCs require a distinct cis-regulatory element to instruct tolerance to …

Zhao(J),Hao(J),Chen(J),Lyu(M),Liu(H),Li(N),S… Nat Commun 2026-02-21

...Rorc gene loci, OCR369 governs RORγt expression in ILC3s and other RORγt+ APCs, but not T cells, through interaction wit...

A hierarchical Rorc(γt) cis-regulatory cascade orchestrates differentiation of …

Fukui(T),Watanabe(M),Kobayashi(R),Yamada(T),… Immunity 2026-04-14

...Rorc locus, which were sequentially utilized during differentiation. Initially, Runx-binding sites in CNS11 established ...

Candida albicans-Based Immune Training to Reduce Lung Fibrosis from Polystyrene…

Zhu(Z),Zhou(Y),Zheng(D),Xu(Z),Chen(Y),Wang(F… Int J Mol Sci 2026-05-07

...Rorc: 1.69-fold, Cry1: 2.01-fold, Per1: 2.55-fold, Per2: 2.73-fold) and one downregulated circadian rhythm gene (Npas2: ...

Unfolding Immune Dysregulation in COPD: Identification of a Three-Gene Signatur…

Wang(Z),Yang(Y),Wang(L),Luo(Z) Int J Mol Sci 2026-05-09

...RORC, TCF7, and CLEC4D) consistently discriminated COPD. CLEC4D localized to myeloid cells, while RORC/TCF7 mapped to ly...

Dried Ginger Milk Extract Alleviates Inflammatory Bowel Disease-Associated Bone…

Li(Y),Liao(X),Wang(C),Bao(X),Liu(Y),Duan(S),… Pharmaceuticals (Basel) 2026-04-26

...Rorc, Tnfα, Ccr2, Ccr6, Cxcr4, Csf1, and Tnfsf11. Compared with aqueous extract, DGME was enriched in 19 lipophilic cons...

TCR γδ cell-specific STAT5 gain of function induces a druggable chronic human i…

Meyer(BJ),Loureiro(JP),Nosi(V),Hupfer(R),Gho… J Hum Immun 2026-09-07

...RORC and MAF expression. The JAK inhibitor baricitinib improved clinical features of the observed immune dysregulation a...

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