...RARA rearrangement is even more rare, with only 12 such APL cases of FISH-negative cryptic PML-RARA rearrangements in th...
...rAra h 9. Combining rAra h 2 and rAra h 9 resulted in high performance of the test with sensitivity, specificity, positi...
...RARA fusion signals. At the second and third relapses, leukemic cells with near-tetraploidy and double PML/RARA fusion s...
...RARA. We hypothesized that this lack of co-operation between PML/RARA and TRIB1 reflected a common pathway for their eff...
...RARA fusion protein, but not PML-RARA mutants defective in transactivation, strongly transactivates the C/EBPbeta promot...
We compared genomic breakpoints at the PML and RARA loci in 23 patients with therapy-related acute promyelocytic leukemi...
...RARA) genes. Rare cryptic fusions often associated with small genomic insertions can best be detected by reverse transcr...
...RARA-amplified, but not RARA-normal, cell lines through apoptosis. Gene expression arrays showed that ATRA-induced apopt...
...RARA) mutational status using Sanger sequencing were evaluated. Overall, eight different types of mutations in the RARA ...
...RARA isoform by reverse transcriptase polymerase chain reaction (RT-PCR). Depending on the PML break point, usually loca...
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