Lehman(N L) Biochimie 1996-03-25

...FPGS, EC 6.3.2.17) levels correlated with cytotoxic potency in a positive manner. Surprisingly, two enzyme-dose/DDATHF L...

Chen(L),Qi(H),Korenberg(J),Garrow(T A),Choi(… J Biol Chem 1996-08-15

...FPGS gene spans 12 kilobases and contains 15 exons and 14 introns. A single FPGS gene was located to chromosome region 9...

Takemura(Y),Kobayashi(H),Gibson(W),Kimbell(R… Int J Cancer 1996-05-29

...FPGS) mRNA was only moderately decreased in the 2 ZD1694-resistant sub-lines and to an even lesser extent in MOLT-3/MTX....

Spinella(M J),Brigle(K E),GoldmanD Biochim Biophys Acta 1996-05-23

...FPGS isolated from L1210 leukemia cells. The amino acid sequence of murine FPGS is 82% identical to human FPGS+[1] with ...

Matsuoka(H),Kato(N),Tsuji(K),Maruyama(N),Suz… Chem Pharm Bull (Tokyo) 1996-09-12

...FPGS) and did not undergo polyglutamation, a process which may be responsible for a side-effect during MTX therapy.

Jackman(A L),Kimbell(R),Brown(M),Brunton(L),… Anticancer Drug Des 1996-01-16

...FPGS) and the reduced-folate cell membrane carrier (RFC). Short-exposure growth-inhibition assays or the measurement of ...

Lenz(H J),Danenberg(K),Schnieders(B),Goeker(… Oncol Res 1995-03-27

...FPGS) cell lines transfected with human DNA and expressing different levels of human FPGS, FPGS gene expression measured...

Egan(M G),Sirlin(S),Rumberger(B G),Garrow(T … J Biol Chem 1995-04-14

...FPGS activity, increase in nitro blue tetrazolium-positive cells, and decline in the level of a 2.1-kilobase FPGS mRNA d...

Westerhof(G R),Schornagel(J H),Kathmann(I),J… Mol Pharmacol 1995-10-30

...FPGS), and thymidylate synthase (TS). Parameters that were investigated included the affinity of both folate-transport s...

Roy(K),Mitsugi(K),Sirlin(S),Shane(B),Sirotna… J Biol Chem 1995-12-26

...FPGS mRNA when compared with control, while Southern blotting of genomic DNA did not reveal any increase in FPGS gene-co...