...RARA DNA probe and whole chromosome paints 15 and 17. A typical PML-RARA fusion transcript consistent with a breakpoint ...
...RARA) gene on chromosome 17 and the PML gene on chromosome 15. We report a patient with typical APL without the common t...
...RARA agonist able to induce myeloid differentiation in these high-expressing RARA AML subtypes. Cancer Discov; 7(10); 10...
...RARA transcript was detected by fluorescence in situ hybridization (FISH) and reverse transcription polymerase chain rea...
...RARA fusion and/or anomalies of the RARA gene (alias RARalpha) in interphase nuclei from patients with acute promyelocyt...
...RARA and RARA-PML. Only one, the PML-RARA, is associated with APL. The PML-RARA chimeric protein has two zinc finger-lik...
...RARA and PML proteins, together with the ligand-binding domain of RARA, are combined in a single fusion protein which ma...
...RARA) gene locus. The presence of a RARA SE and concomitant high levels of RARA mRNA predisposes cell lines and ex vivo ...
Most acute promyelocytic leukemia (APL) are caused by PML-RARA, a translocation-driven fusion oncoprotein discovered thr...
...RARa, and cyclin-D was tested on a uterine leiomyoma. C-myc and RARa were amplified in approximately 30% and 90% of the ...
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