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New cytogenetic variant, insertion (15;17)(q22;q12q21), in an adolescent with a…

Rolston(R),Weck(KE),Tersak(JM),Sherer(ME),Cu… Cancer Genet Cytogenet 2002-04-01

...RARA DNA probe and whole chromosome paints 15 and 17. A typical PML-RARA fusion transcript consistent with a breakpoint ...

Rearrangements of the RARA and PML genes in a cytogenetic variant of acute prom…

Baranger(L),Gardembas(M),Hillion(J),Foussard… Genes Chromosomes Cancer 1993-02-00

...RARA) gene on chromosome 17 and the PML gene on chromosome 15. We report a patient with typical APL without the common t...

Targeting the Noncoding Genome: Superenhancers Meet Their Kryptonite.

Wang(E),Aifantis(I) Cancer Discov 2017-00-00

...RARA agonist able to induce myeloid differentiation in these high-expressing RARA AML subtypes. Cancer Discov; 7(10); 10...

[Therapy-related acute promyelocytic leukemia with complex karyotype accompanie…

Kashima(E),Sugimoto(Y),Nato(Y),Ino(K),Tawara… Rinsho Ketsueki 2020-00-00

...RARA transcript was detected by fluorescence in situ hybridization (FISH) and reverse transcription polymerase chain rea...

New highly sensitive fluorescence in situ hybridization method to detect PML/RA…

Brockman(SR),Paternoster(SF),Ketterling(RP),… Cancer Genet Cytogenet 2003-09-00

...RARA fusion and/or anomalies of the RARA gene (alias RARalpha) in interphase nuclei from patients with acute promyelocyt...

Cytogenetics, gene fusions, and cancer.

Glassman(AB) Ann Clin Lab Sci 1995-00-00

...RARA and RARA-PML. Only one, the PML-RARA, is associated with APL. The PML-RARA chimeric protein has two zinc finger-lik...

Molecular analysis of the t(15;17) translocation in acute promyelocytic leukaem…

Borrow(J),Solomon(E) Baillieres Clin Haematol 1992-10-00

...RARA and PML proteins, together with the ligand-binding domain of RARA, are combined in a single fusion protein which ma...

Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Includ…

McKeown(MR),Corces(MR),Eaton(ML),Fiore(C),Le… Cancer Discov 2017-00-00

...RARA) gene locus. The presence of a RARA SE and concomitant high levels of RARA mRNA predisposes cell lines and ex vivo ...

Classic and Variants APLs, as Viewed from a Therapy Response.

Geoffroy(MC),de Thé(H) Cancers (Basel) 2020-04-14

Most acute promyelocytic leukemia (APL) are caused by PML-RARA, a translocation-driven fusion oncoprotein discovered thr...

Fluorescence in situ hybridization of three oncogenes on a leiomyoma.

Faruqi(SA),Saquib(M),Harsch(C),Noumoff(JS) Microsc Res Tech 2012-08-00

...RARa, and cyclin-D was tested on a uterine leiomyoma. C-myc and RARa were amplified in approximately 30% and 90% of the ...

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