McDonald(D),Atkinson(I J),Cossins(E A),Shane… Phytochemistry 1995-07-10

The possible association of dihydrofolate synthetase (DHFS) and folylpolyglutamate synthetase (FPGS) in Neurospora crass...

Gangjee(A),Devraj(R),McGuire(J J),Kisliuk(R … J Med Chem 1995-10-25

...FPGS) derived from CCRF-CEM cells (Km 8.5 microM). Further evaluation of the growth inhibitory activity of 3 against the...

Gangjee(A),Devraj(R),McGuire(J J),Kisliuk(R … J Med Chem 1995-12-26

...FPGS derived from CCRF-CEM cells. Compound 5 was cytotoxic to CCRF-CEM and FaDu tumor cell lines as well as to an FPGS-d...

Westerhof(G R),Schornagel(J H),Kathmann(I),J… Mol Pharmacol 1995-10-30

...FPGS), and thymidylate synthase (TS). Parameters that were investigated included the affinity of both folate-transport s...

Roy(K),Mitsugi(K),Sirlin(S),Shane(B),Sirotna… J Biol Chem 1995-12-26

...FPGS mRNA when compared with control, while Southern blotting of genomic DNA did not reveal any increase in FPGS gene-co...

Lenz(H J),Danenberg(K),Schnieders(B),Goeker(… Oncol Res 1995-03-27

...FPGS) cell lines transfected with human DNA and expressing different levels of human FPGS, FPGS gene expression measured...

Egan(M G),Sirlin(S),Rumberger(B G),Garrow(T … J Biol Chem 1995-04-14

...FPGS activity, increase in nitro blue tetrazolium-positive cells, and decline in the level of a 2.1-kilobase FPGS mRNA d...

Jackman(A L),Gibson(W),Brown(M),Kimbell(R),B… Adv Exp Med Biol 1994-06-07

...FPGS. For example, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolate (ICI 198583) owes its less potent cytotoxic activ...

Barredo(J C),Synold(T W),Laver(J),Relling(M … Blood 1994-08-11

...FPGS expression, FPGS activity increased in ALL blasts after in vivo exposure to MTX. The median increase in FPGS activi...

Lin(B F),Shane(B) J Biol Chem 1994-05-05

...FPGS to the mitochondria of these cells. Mitochondrial expression of FPGS restored mitochondrial folylpolyglutamate pool...