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Traumatic brain injury has a lasting impact on hippocampal neurogenesis and Not…

Weston(NM),Keoprasert(TN),Green(JC),Baig(S),… bioRxiv 2026-02-05

...Notch1 was conditionally deleted from nestin+ NSCs. We also found that injury and Notch1 deletion drove NSCs committing ...

From heterogeneity to molecular stratification: A multiplex genomic panel for t…

Margoni(A),Papavassiliou(KA),Papavassiliou(A… Oral Oncol 2026-04-00

...NOTCH1-3, FAT atypical cadherin 1 (FAT1)), HPV-associated oncogenic drivers (phosphatidylinositol-4,5-bisphosphate 3-kin...

Glutamine alleviates radiation-induced intestinal injury in rats via the mTOR/N…

Lu(H),Ni(X),Liang(X),Bai(Q),Li(H),Shi(M),Jia… Front Oncol None

...Notch1. Pharmacologic interventions using rapamycin and Jagged-1 further validated that Gln modulates the mTOR/Notch1 si...

JAG1 expression in papillary thyroid cancer stem-like cells predicts poor progn…

Yoshida-Minato(R),Horie(T),Aga(M),Sakamoto(T… Discov Oncol 2026-02-09

...NOTCH1/4 in endothelial cells. Analysis of clinical data showed that thyroid cancer patients with high stemness exhibiti...

ZP3 promotes hepatocellular carcinoma progression via the Notch signaling pathw…

Qu(C),Yan(X),Li(Y) World J Surg Oncol 2026-02-09

...Notch1, NICD1, and Hes1), whereas ZP3 overexpression activated this pathway. ZP3 expression was significantly correlated...

Notch receptors in breast cancer: context-dependent roles and therapeutic targe…

Wang(M),Mi(Y),Ye(Q) Cell Commun Signal 2026-07-17

...Notch1-4 display nonredundant functional divergence in BC. In this review, we discuss how receptor-specific regulatory m...

Whole-exome sequencing identifies matrisomal gene associations in monogenic cer…

Guyler(SK),Alfayyadh(MM),Maksemous(N),Lea(RA… J Neurol 2026-07-21

...NOTCH1 (adjusted P = 1 × 10-2). We further identified novel associations for seven genes (COL7A1, HMCN1, LAMA1, MMP9, TE...

Total saponins of Trillium tschonoskii Maxim. mitigate locomotor deficits assoc…

Wang(H),Xiao(Z),Wang(T),Jia(J),Lei(J),Zhuang… J Ethnopharmacol 2026-10-28

...Notch1/Hes5 signaling axis were analyzed via immunofluorescence and western blotting. TSTT treatment significantly atten...

Multidimensional Proteomics Reveals the Pro-apoptotic Mechanism of Platycodin D…

Zhang(H),Zhou(B),Liu(J),Ren(Y) Mol Cell Proteomics 2026-08-00

...Notch1 and Notch3 by reducing nuclear entry of their domains. Compared with control treatment, the differentially expres...

Notch signaling in the embryonic ectoderm promotes periderm cell fate and repre…

Zhao(D),Ozekin(Y),Binne(E),Choi(I),Taiyab(A)… bioRxiv 2026-01-30

...Notch1 intracellular domain. Loss of Rbpj resulted in cleft secondary palate but strikingly was also associated with the...

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