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[Possible association due to linkage disequilibrium of TGFA, RARA and BCL3 with…

Suazo(J),Santos(JL),Silva(V),Jara(L),Palomin… Rev Med Chil 2005-09-00

...RARA and BCL3 have been postulated as being involved in the genetic etiology of this pathology. To test the possible ass...

Two new 3' PML breakpoints in t(15;17)(q22;q21)-positive acute promyelocytic le…

Chillón(MC),González(M),García-Sanz(R),Balan… Genes Chromosomes Cancer 2000-01-00

In the present article, two new types of PML/RARA junctions are described. Both were identified in diagnostic samples fr...

ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate wi…

Lucena-Araujo(AR),Coelho-Silva(JL),Pereira-M… Oncotarget 2017-01-31

Here, we evaluated whether the overexpression of transcriptionally inactive ΔNp73 cooperates with PML/RARA fusion protei...

3D Mammary Epithelial Cell Models: A Goldmine of DCIS Biomarkers and Morphogene…

Rossetti(S),Sacchi(N) Cancers (Basel) 2019-01-23

...RARA) transcriptional function, but retain the RARA function controlling the PI3KCA-AKT signaling, develop 3D "DCIS-like...

Acute Promyelocytic Leukemia: Update on the Mechanisms of Leukemogenesis, Resis…

Noguera(NI),Catalano(G),Banella(C),Divona(M)… Cancers (Basel) 2019-10-18

...RARa) sets the cellular landscape of acute promyelocytic leukemia (APL) by repressing the transcription of RARa target g...

Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA d…

Bian(Y),Xue(M),Guo(X),Jiang(W),Zhao(Y),Zhang… Pharm Biol 2022-12-00

...RARA) fusion protein. Cinobufagin (CBG) is one of the main effective components of toad venom with antitumor properties....

Relapse of acute promyelocytic leukemia follows serial negative RT-PCR assays: …

Devaraj(PE),Foroni(L),Prentice(GH),Hoffbrand… Leuk Res 1996-09-00

...RARA. The clone was detected in remission following all-trans retinoic acid and chemotherapy by cytogenetics and/or by R...

Variant acute promyelocytic leukemia translocation (15;17) originating from two…

Tirado(CA),Jahn(JA),Scheerle(J),Eid(M),Meist… Cancer Genet Cytogenet 2005-08-00

...RARA fusion, it is useful and necessary to perform both cytogenetic and FISH analyses of a variant t(15;17) to determine...

Identification of a novel RAB6A::TOP2A fusion in acute non-promyelocytic leukem…

Su(Z),Du(Y),Yuan(C),Zhao(X),Zhang(X),Cui(H),… Virchows Arch 2025-06-00

Fusion genes generally serve as driver mutations in leukemia. The rearrangement of the RARA gene located on chromosome 1...

Specific expression of the annexin VIII gene in acute promyelocytic leukemia.

Chang(KS),Wang(G),Freireich(EJ),Daly(M),Nayl… Blood 1992-04-01

...RARA) gene, the expression of many genes normally regulated by RARA may be affected by this translocation. To identify g...

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