...FPGS from mammalian sources (rat, hog, mouse, and beef liver). Kinetic constants for the substrates and activators of FP...
...FPGS) from mouse liver (Ki = 0.15 +/- 0.06 microM). The MTX analogue (mAPA-Orn) was likewise active against both enzymes...
...FPGS). This auxotroph and others like it contain less than 3% of the parental amounts of FPGS activity. In order to deve...
...FPGS) is activated by addition of pteroic acid. Pteroic acid causes greater stimulation of FPGS, including glutamylation...
...FPGS. The activities of folate and antifolate substrates also have been determined with rat liver FPGS. With near-satura...
...FPGS) has been investigated. MeAPA-Glu and MeAPA-Glu-Glu were accepted as substrates by the same FPGS species contained ...
...FPGS. The pattern of polyglutamate products synthesized by rat liver FPGS was nearly identical with both 7-hydroxymethot...
...FPGS) was assigned to mouse chromosome 2 by complementation mapping. Chinese hamster ovary cells (AuxBl) deficient in FP...
...FPGS in the hybrids, but also demonstrated that several enzyme characteristics of FPGS in the hybrids are consistent wit...
...FPGs) in parsley, carrot and Arabidopsis. This is thought to allow the plant focusing its secondary metabolism on the pa...
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