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Expression of methotrexate transporters and metabolizing enzymes in rheumatoid …

Stamp(Lisa K),Hazlett(Jody),Highton(John),He… J Rheumatol 2014-06-09

...FPGS)], and mechanism of action of MTX [thymidylate synthase, MTR, MTRR] in rheumatoid synovium.,Synovial tissue samples...

FPGS rs1544105 polymorphism is associated with treatment outcome in pediatric B…

Liu(Shu-Guang),Gao(Chao),Zhang(Rui-Dong),Jia… Cancer Cell Int 2014-01-16

...FPGS transcripts.,Our study indicates that FPGS rs1544105C > T polymorphism might influence FPGS expression and affect t...

Targeted expression of human folylpolyglutamate synthase for selective enhancem…

Bienemann(K),Staege(M S),Howe(S J),Sena-Este… Cancer Gene Ther 2014-04-08

...fpgs and the gene for enhanced green fluorescent protein (egfp), which was linked to fpgs by an internal ribosomal entry...

[Correlation analysis of FPGS rs10760502G>a polymorphism with prognosis and MTX…

Liu(Shu-Guang),Gao(Chao),Li(Zhi-Gang),Li(Wei… Zhongguo Shi Yan Xue Ye Xue Z… 2014-09-04

This study was aimed to explore the relation between folylpolyglutamate synthetase (FPGS) rs10760502 polymorphism and pr...

Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexat…

Wang(Shu-mei),Sun(Lu-lu),Zeng(Wei-xin),Wu(Wa… Cancer Chemother Pharmacol 2014-10-28

To investigate the correlation between common genetic polymorphisms of folylpolyglutamate synthase (FPGS), gamma-glutamy...

Humanizing mouse folate metabolism: conversion of the dual-promoter mouse folyl…

Yang(Chen),Xie(Lin-Ying),Windle(Jolene J),Ta… FASEB J 2014-06-16

...fpgs gene structure. Despite the loss of the predominant fpgs mRNA species in liver and kidney (representing 95 and 75% ...

Genetic variant in folate homeostasis is associated with lower warfarin dose in…

Daneshjou(Roxana),Gamazon(Eric R),Burkley(Be… Blood 2014-12-04

...FPGS). We replicated this association in an independent cohort of 372 African American subjects whose stable warfarin do...

Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain th…

Lawrence(Scott A),Titus(Steven A),Ferguson(J… J Biol Chem 2014-12-22

...FPGS) catalyze the addition of multiple glutamates to tetrahydrofolate derivatives. Two mRNAs for the fpgs gene direct i...

The reliability of in-hospital diagnoses of diabetes mellitus in the setting of…

Arnold(Suzanne V),Lipska(Kasia J),Inzucchi(S… BMJ Open Diabetes Res Care 2014-12-02

...FPGs recorded during hospitalization. We examined potential combinations of RPG and FPG and compared these with HbA1c≥6....

Folic acid pathway single nucleotide polymorphisms associated with methotrexate…

Davis(L A),Polk(B),Mann(A),Wolff(R K),Kerr(G… Clin Exp Rheumatol 2014-08-12

...FPGS], gamma-glutamyl hydrolase [GGH], and methylenetetrahydrofolate reductase [MTHFR]) associate with significant adver...

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