Ivaskevicius(Vytautas),Windyga(Jerzy),Bara... Blood Coagul Fibrinolysis 2008-11-24

...MCFD2 genes. Here we report the first Polish family with F5F8 deficiency due to a mutation in the MCFD2 gene. The propos...

Kawasaki(Norihito),Ichikawa(Yoko),Matsuo(I... Blood 2008-05-21

...MCFD2. LMAN1 encodes ERGIC-53, a cargo receptor with an L-type lectin domain, and MCFD2 is a EF-hand-containing protein....

Zhang(Bin),Spreafico(Marta),Zheng(Chunlei)... Blood 2008-07-15

...MCFD2 and 2 in LMAN1. We show that a novel MCFD2 missense mutation identified here (D81Y) and 2 previously reported muta...

Guy(Jodie E),Wigren(Edvard),Svärd(Maria),H... J Mol Biol 2008-09-05

...MCFD2 in the secretory pathway is comparatively unclear. MCFD2 has been shown to bind both ERGIC-53 and the blood coagul...

Baines(Andrea C),Zhang(Bin) Trends Biochem Sci 2007-10-15

...MCFD2 complex, is required for the efficient secretion of coagulation factors V and VIII. Studies of this complex, coupl...

Nyfeler(Beat),Zhang(Bin),Ginsburg(David),K... Traffic 2007-01-03

...MCFD2 by short interference RNA-based knockdown. In the absence of ERGIC-53, MCFD2 was secreted, whereas knocking down M...

Zhang(Bin),McGee(Beth),Yamaoka(Jennifer S)... Blood 2006-04-03

...MCFD2 cause combined deficiency of factor V and factor VIII (F5F8D). LMAN1 and MCFD2 form a protein complex that functio...

Zhang(B),Ginsburg(D) J Thromb Haemost 2005-02-14

...MCFD2) that encode components of a stable protein complex. This complex is localized to the secretory pathway of the cel...

Nyfeler(Beat),Michnick(Stephen W),Hauri(Ha... Proc Natl Acad Sci U S A 2005-08-01

...MCFD2, and to ERGIC-53's cargo glycoprotein cathepsin Z. YFP PCA analysis revealed the oligomerization of ERGIC-53 and i...

Zhang(Bin),Kaufman(Randal J),Ginsburg(Davi... J Biol Chem 2005-08-16

...MCFD2 are present primarily in complex with each other with a 1:1 stoichiometry, although MCFD2 is not required for olig...