...MCFD2 axis that governs the folding and secretion of NlCSP1. NlGRP94 and NlGRP78 act as chaperones, and NlLMAN1-NlMCFD2 ...
...MCFD2, leading to combined F5 and F8 deficiency. Rarely, it can be of digenic inheritance with separate defects in F5 an...
...MCFD2 and down-regulated E4F1 and PDCD2 had an association with tissue homeostasis for TCs. Over-expressed Dpysl3 may pr...
...MCFD2-LMAN1 complex. Here, we have investigated the solution conformations of the MCFD2((D81H,V100D)) protein mutant thr...
...MCFD2 as causative genes for this disorder, revealing a previously unknown intracellular transport pathway shared by the...
...MCFD2 and the α1,2 mannotriose which corresponds to the trisaccharide of the D1 arm of high-mannose-type glycans. ERGIC-...
...MCFD2 genes. Mutations in LMAN1 was confirmed by molecular cloning of the PCR product and resequencing of the resulting ...
...MCFD2 is involved in the secretion of Mac-2BP. These observations reveal a distinct role for the N-glycan binding of ERG...
...MCFD2) are a cause of factor V and factor VIII combined deficiency type 2 (F5F8D). MCFD2 was also suggested to play an i...
...MCFD2, LMAN1 transports coagulation factors V (FV) and VIII (FVIII). Mutations in LMAN1 or MCFD2 cause the genetic bleed...
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