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Islam(R),Zhang(F),Choudhary(HH),Yoshida(J)... J Neuroinflammation 2026-02-19

...Lyn kinase; Lyn was increasing the threshold for TRPV4 responsiveness to LPS. To translate these findings to an in vivo ...

Bal Albayrak(MG),Yanar(S),Korak(T),Akpinar... Med Oncol 2026-03-03

...LYN-1604 or inhibitor MRT68921 at EC₅₀ concentrations. Autophagic activity, validated through LC3B immunoblotting and fl...

Fiske(BE),Wemlinger(SM),Crute(BW),Getahun(... Nat Commun 2026-03-08

...Lyn in B cell and myeloid cell development and activation is challenging. Here we utilize a system in which Lyn deletion...

Wang(Y),Yuan(Y),Luo(S),Wang(C),Gong(L),Du(... Br J Pharmacol 2026-06-00

...Lyn kinase inhibitor, blocking Ag/IgE-induced mast cell degranulation. By binding to Lyn, ALA disrupted the FcεRIβ-Lyn i...

Qu(X),Zuo(X),Du(H),Chen(Y),Zhang(Q),Peng(H... Medicine (Baltimore) 2026-02-27

...LYN, TLR1, TLR2, TLR8, FCGR1A, FCGR2A, CCR1, CXCL1, FPR1, and SELL) were considered as neutrophil-related genes. Mechani...

Yan(PP),Huang(TT),Attiogbe(MKI),Mi(YN),Cao... Toxicol Appl Pharmacol 2026-05-00

...Lyn kinase activation and suppressed SP-and Tween 80-induced β-hexosaminidase release, exhibiting an inhibitory profile ...

Chen(T),Yang(YR),He(MH),Zhang(X),Liao(SG),... Fitoterapia 2026-03-00

...LYN kinase (a key BCR pathway target) throughout 100 ns simulations. In summary, BT demonstrates substantial hepatoprote...

Wang(C),Wu(H),Zheng(C),Zhang(H),Wu(X),Wang... Adv Sci (Weinh) 2026-08-00

...LYN-SH domains, facilitating the ternary complex formation that enhances LYN-mediated STAT3 phosphorylation, ultimately ...

Li(R),Xie(J),Li(Q),Ouyang(Y),Zhang(Q),Wang... Neurochem Res 2026-05-20

...Lyn, Syk and ERK. Knockout of Treml4 significantly reversed the phosphorylation of Lyn, Syk, and ERK in the hippocampus,...

Koldamova(R),Fitz(NF),Lefterov(I) Neuron 2026-08-05

...Lyn, and Fcgr1, providing new insight into PU.1-dependent regulatory networks and microglial functions in neurodegenerat...