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Cbfb2 gene dosage programs the differential lymphoid lineage developmental pote…

Berthelette(A),Newell(K),Phan(Q),Taniuchi(I)… bioRxiv 2026-03-05

...Notch1 haploinsufficiency enhanced Tγδ17 generation and phenocopied the effect of CBFβ2 dosage reduction, linking quanti...

[Psoralen inhibits liver metastasis of colorectal cancer by regulating Notch/Sn…

Gu(XM),Yang(SX),Song(JM) Zhongguo Zhong Yao Za Zhi 2026-06-00

...Notch1 and Snail were measured. Mice were assigned into a normal group, a model group, low-, medium-, and high-dose psor...

[Mechanism of traditional Chinese medicine Xinfeng Capsules in improving pulmon…

Li(MQ),Wang(DL),Fang(W),Zhu(WT),Wei(WB),Yan(… Zhongguo Zhong Yao Za Zhi 2026-07-00

...Notch1), Jagged canonical Notch ligand 1(Jagged1), nuclear factor of activated T cells cytoplasmic 1(NFATC1) and interfe...

NOTCH1 gene signaling pathway in the development and progression of carcinomas:…

Silva(LMSD),Matos(AGM),Kwang Ii Marciaga Teó… Cell Mol Biol (Noisy-le-grand) 2026-04-30

...notch1 alterations on tumor behavior and clinical outcomes. NOTCH1 functions as a context-dependent regulator, acting ei...

Tryptophan metabolism reprogramming regulates Th1/Th2 immune balance and inhibi…

Huang(D),Huang(D),Su(L),He(C),Zhang(X),Peng(… Amino Acids 2026-02-28

...Notch1/Jagged1 levels and elevated IL-2 and IFN-γ, while IL-4 expression was reduced. RT-qPCR showed upregulated T-bet a...

CACUL1 promotes hepatocellular carcinoma progression through enhanced tumor cel…

Wang(X),Tan(Y),Wang(J),Kong(Y) Front Immunol None

...Notch1 suppression, with pharmacological Notch inhibition phenocopying this effect. CACUL1 functions as a dual-axis onco...

Dysregulated lipid metabolites GML and GMO were associated with cytotoxic T cel…

Guo(T),Gao(W),Zhang(A),Wang(D),Zhao(Y),Li(Y)… Front Immunol None

...Notch1 signaling and cytotoxic protein expression in T cells. ROC curve analyses were performed to evaluate the diagnost...

Jiawei Taohe Chengqi decoction improves intestinal barrier damage in sepsis by …

Zhu(H),Guo(D),Qian(S) Cell Immunol 2026-09-00

...Notch1, Jagged1 and HES1 was assessed by western blot. Immunofluorescence was applied to assess the expression of F4/80,...

The Role of the Notch1 Signaling Pathway in the Pathogenesis and Treatment of D…

Zhi(Y),Weiqi(H),Caibo(Z),Binqi(C),Duo(Z),Lan… Diabetes Ther 2026-07-24

...Notch1 signaling pathway is highly conserved and participates in regulating cell proliferation, differentiation, apoptos...

PTPN14 functions as an oncogenic promoter in colon adenocarcinoma and liver hep…

Wang(Y),Li(J),Wang(C),Zhang(H),Sun(Z),Chang(… Cell Signal 2026-11-00

...Notch1 by competitively binding to prevent FBXW7-mediated ubiquitination, and increasing the expression of Notch1 intrac...

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