...Notch1 haploinsufficiency enhanced Tγδ17 generation and phenocopied the effect of CBFβ2 dosage reduction, linking quanti...
...Notch1 and Snail were measured. Mice were assigned into a normal group, a model group, low-, medium-, and high-dose psor...
...Notch1), Jagged canonical Notch ligand 1(Jagged1), nuclear factor of activated T cells cytoplasmic 1(NFATC1) and interfe...
...notch1 alterations on tumor behavior and clinical outcomes. NOTCH1 functions as a context-dependent regulator, acting ei...
...Notch1/Jagged1 levels and elevated IL-2 and IFN-γ, while IL-4 expression was reduced. RT-qPCR showed upregulated T-bet a...
...Notch1 suppression, with pharmacological Notch inhibition phenocopying this effect. CACUL1 functions as a dual-axis onco...
...Notch1 signaling and cytotoxic protein expression in T cells. ROC curve analyses were performed to evaluate the diagnost...
...Notch1, Jagged1 and HES1 was assessed by western blot. Immunofluorescence was applied to assess the expression of F4/80,...
...Notch1 signaling pathway is highly conserved and participates in regulating cell proliferation, differentiation, apoptos...
...Notch1 by competitively binding to prevent FBXW7-mediated ubiquitination, and increasing the expression of Notch1 intrac...
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