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[A novel missense mutation of folypolyglutamate synthetase gene].

Hu(Chun-Yan),Yue(Li-Jie),Yu(Jie),Zhang(Hong-… Zhongguo Dang Dai Er Ke Za Zhi 2012-10-25

To examine allelic frequencies of coding single nucleotide polymorphisms (cSNPs) of folypolyglutamate synthetase (FPGS) ...

[The mbr-FPGS efficient expression plasmid enhances the sensitivity of Jurkat c…

Hu(Wen-Jia),Sun(Yu-Jie) Yi Chuan 2012-09-20

...FPGS) is the key enzyme that converts chemotherapy drug Methotrexate (MTX) into MTXPG. The expression level of FPGS dire...

Intracellular disposition of methotrexate in acute lymphoblastic leukemia in ch…

de Beaumais(Tiphaine Adam),Jacqz-Aigrain(Eve… Curr Drug Metab 2012-11-27

...FPGS). Long chain MTXPG have higher affinity than MTX for the enzymes involved in de novo purine synthesis such as 5-ami...

Evaluation of candidate reference genes for qPCR in maize.

Manoli(Alessandro),Sturaro(Alba),Trevisan(Sa… J Plant Physiol 2012-08-09

...FPGS, LUG, MEP and UBCP) exhibited the highest expression stability according to all algorithms. In conclusion, with thi...

Implementation of FocalPoint GS location-guided imaging system: experience in a…

Levi(Angelique W),Chhieng(David C),Schofield… Cancer Cytopathol 2012-06-01

...FPGS implementation. We also retrieved all SurePath specimens from a 16-month period prior to FPGS implementation to ser...

Relationships between hemoglobin A 1c and spot glucose measurements in Nigerian…

Edo(A E),Akhuemokhan(K) Niger J Clin Pract 2012-09-19

...FPGs of diabetic subjects from the mean of their monthly FPGs of the preceding three months. Other data extracted includ...

Safety and efficacy of pralatrexate in the management of relapsed or refractory…

Rodd(Annabelle L),Ververis(Katherine),Karagi… Clin Med Insights Oncol 2012-10-04

...FPGS). RFC is the principal transporter for cell entrance of folates and antifolates. Once inside the cell, pralatrexate...

Biomarker analysis in a phase III study of pemetrexed-carboplatin versus etopos…

Smit(E F),Socinski(M A),Mullaney(B P),Myrand… Ann Oncol 2012-10-22

...FPGS) were investigated using IHC (n=395). SNPs were genotyped for TS, FPGS, γ-glutamyl hydrolase (GGH), methylenetetrah...

Genetic variation in folylpolyglutamate synthase and gamma-glutamyl hydrolase a…

Oppeneer(Sarah J),Ross(Julie A),Koh(Woon-Pua… Mol Genet Metab 2012-05-31

The enzymes folylpolyglutamate synthase (FPGS) and gamma-glutamyl hydrolase (GGH) are essential for determining intracel...

Alcohol-associated folate disturbances result in altered methylation of folate-…

Wani(Nissar Ahmad),Hamid(Abid),Kaur(Jyotdeep) Mol Cell Biochem 2012-07-02

...FPGS), which adds glutamate residues, and gamma-glutamyl hydrolase (GGH), which removes them, enabling it to be transpor...

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