...RARA moiety of the fusion, whereas arsenic targets its PML part. PML/RARA expression in the mouse is sufficient to initi...
...RarA-mVenus fusion to visualize the dynamics of RarA during conditions that generate DNA damage. In exponentially growin...
...RarA function. Further work revealed that most of the effects reflected the presence of sequences in the rarA gene that ...
...rarA ΔrecU and ΔrarA ΔrecX double mutant cells, and was blocked in ΔrarA recF15 cells. These results suggest that RarA c...
...RARA was found to possess common features with other RARA fusion proteins. These included: (1) the same break point in R...
...RARa - isoforms RARa and RARa - in pathogenesis of solid and non-solid tumors, including multiple myeloma. The actual da...
...RARA-PML fusion was not evident by FISH, but the RARA signal was split in 74.5% of cells. GTL-banding and FISH with prob...
...RARA moieties of PML/RARA homodimers. Unexpectedly, we show that the K160 sumoylation site in the PML moiety of PML/RARA...
...RARA rearrangement (including 94 with PML-RARA and one with NPM-RARA) and two samples with KMT2A rearrangement. In the e...
...RARA mutants, were deficient in colony formation. Further experiments showed that DNA-binding-defective PML/RARA mutants...
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