...FPGS, GGH, NME1, NT5C, RRM1, TYMS, UCK2, UNG and UMPS).,The RNAi screening strategy enabled prioritization of the genes ...
...FPGS) catalyzes the attachment of glutamate residues to the folate molecule in plants. Three isoforms of FPGS have been ...
...FPGS) gene expression, low gamma-glutamyl hydrolase (GGH) gene expression and low ATP-binding cassette sub-family C, num...
...FPGS) and blocks folate metabolism and DNA synthesis by inhibiting TS, dihydrofolate reductase (DHFR) and glycinamide ri...
...FPGS) are key elements in the folate pathway. The role of FPGS is to add glutamate residues to folates and antifolates, ...
...FPGS) as a single bifunctional protein. The two activities contribute to the essential pathway of folate biosynthesis an...
...FPGS) genes. TS gene expression was significantly increased in PC6/MTA-1.6 and PC6/MTA-4.0 cells relative to parental ce...
...FPGS and other folate-related genes. HDACIs increased FPGS mRNA expression by 2- to 5-fold, whereas DHFR and TS mRNA exp...
...FPGS, GGH and SLC19A1, using 1,750 population-based and 245 clinic-based cases of pathologically confirmed colorectal ca...
...FPGS, GGH, and SLC19A1 genes. Patients with various genotypes were compared for efficacy and adverse events resulting fr...
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