Muegge(Ingo),Collin(Delphine),Cook(Brian),Hi… Bioorg Med Chem Lett 2016-02-19

...RORC inverse agonists. The early RORC SAR compound 14 exhibited RORC inhibition in a cell based reporter gene assay of 5...

Liu(Zhi),Cao(Wei),Xu(Longxia),Chen(Xi),Zhan(… J Mol Cell Biol 2016-08-12

...Rorc, which encodes the master Th17 transcription factor Rorγt, and Th17 cytokine genes such as Il17, Il17f, and Il22. T...

Paulissen(Sandra M J),van Hamburg(Jan Piet),… Cytokine 2016-02-19

...RORC. In RA, CCR6+ Th cells were identified in peripheral blood, synovial fluid and inflamed synovial tissue. CCR6+ Th c...

Wu(Shouzhen),Zhang(Xiaoyan),Zhou(Nan) Xi Bao Yu Fen Zi Mian Yi Xue … 2016-03-07

...RORC and IL-17A, but not with IL-6.,SGK1 was up-regulated in CD4⁺ T cells and was positively correlated with RORC and IL...

Espósito(Danillo Lucas Alves),Bollela(Valdes… Lung 2016-08-23

...RORC genes, which showed a statistically higher level in TB. All cytokines in the Th17 pattern were induced in TB patien...

Li(Wentian),Espinal-Enríquez(Jesús),Simpfend… Comput Biol Chem 2016-09-26

...RORC, BCL6, and FOXP3). We compiled a list of genes functionally interacting (protein-protein interaction, or by acting ...

Azevedo(Michelle de C S),Rosa(Patricia S),So… PLoS One 2016-08-17

...RORC, IL-17A, IL-17F, and IL-22 and to compare these levels to those of healthy control skin (N = 12). The results showe...

Zhang(Wenjing),Tian(Xinli),Mumtahana(Fidia),… BMC Cancer 2016-06-29

...RORC), TNF-α and IL-6 were respectively determined. Using the method of ELISA, plasma concentrations of IL-22, IL-17 and...

El-Karaksy(Safaa M),Raafat(Hala A),Abadir(Ma… J Recept Signal Transduct Res 2016-11-14

...RORC mRNA was performed by real-time polymerase chain reaction.,The results showed that patients with SLE had lower RORC...

Olsson(Roine I),Xue(Yafeng),von Berg(Stefan)… ChemMedChem 2016-09-19

...RORc, RORγ), has been identified as the master regulator of T-helper 17 (TH 17) cell function and development, making it...