...SPOP have been observed in various tumor types with chromosomal aberrations, indicating a role of SPOP in maintaining ge...
...SPOP (5.7-10%). However, how SPOP mutations contribute to endometrial cancer remains unknown. Here, we identified estrog...
...SPOP prevent CRL3(SPOP)-dependent degradation of ERG in prostate cancer cells.
...sPOP), urinary incontinence or surgery (UI) and fecal incontinence or surgery (FI).,When caesarean delivery was compared...
...SPOP. Accumulating data suggests that prostate cancer can be subdivided based on a molecular profile of these genetic al...
...SPOP, TP53, ATM, MEN1, NBPF10, NCOR2, PIK3CB and MAP2K5 (MEK5) genes.,Using the methods presented here, NGS technologies...
...SPOP-mediated destruction, whereas prostate cancer-associated SPOP mutants are also deficient in promoting ERG ubiquitin...
...SPOP mutations abrogate the SPOP-mediated degradation function on the ERG oncoprotein. Conversely, the majority of TMPRS...
...SPOP mutations. By reviewing the associations between the morphologic features and the molecular genetics of prostate ca...
...SPOP. SPOP interacts with PR in vivo and targets PR for ubiquitin-dependent proteasomal degradation. Moreover, SPOP supp...
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