Literature Search

Chung(JS),Zhu(JK),Bressan(RA),Hasegawa(PM),S… Plant J 2008-02-00

...SOS1 mRNA. Furthermore, mutations in the SOS1 gene render sos1 mutants more tolerant to paraquat, a non-selective herbic...

Lu(KK),Song(RF),Guo(JX),Zhang(Y),Zuo(JX),Che… Plant Cell 2023-00-26

...SOS1 promoter and activate SOS1 expression. In contrast to the cycc1;1 mutant, the wrky75 mutant has attenuated SOS1 exp...

Furuta(S),Miura(K),Copeland(T),Shang(WH),Osh… Oncogene 2002-10-10

...Sos1. These findings suggest that LC3 interacts with Sos1 and thereby negatively regulates the Sos1-dependent Rac1 activ...

Hwang(HS),Hwang(SG),Cho(JH),Chae(JS),Yoon(KW… J Cell Biol 2011-10-31

...SOS1. CIIA promoted the SOS1-Rac1 interaction and inhibited the SOS1-Ras interaction. Furthermore, CIIA promoted the for...

Baltanás(FC),Pérez-Andrés(M),Ginel-Picardo(A… Mol Cell Biol 2013-11-00

...Sos1-null mouse strain allowing analysis of the combined disruption of Sos1 and Sos2 (Sos1/2) during adulthood. Sos1/2 d...

Liceras-Boillos(P),García-Navas(R),Ginel-Pic… Oncogene 2016-00-15

...Sos1-null mutation, we analyzed wild-type (WT), single Sos1-KO, Sos2-KO and double Sos1/2 KO primary mouse embryonic fib...

Jiang(H),Fan(Y),Wang(X),Wang(J),Yang(H),Fan(… Bioorg Med Chem Lett 2023-00-15

...SOS1) I-5 (IC50 = 18 nM, against SOS1) and I-10 (IC50 = 8.5 nM, against SOS1) have kinase activity equivalent to BAY-293...

Kortum(RL),Sommers(CL),Alexander(CP),Pinski(… Proc Natl Acad Sci U S A 2011-07-26

...Sos1, Sos2, and RasGRP1. We report the development of a floxed allele of sos1 to assess the role of Sos1 during thymocyt...

Bian(Y),Alem(D),Beato(F),Hogenson(TL),Yang(X… J Med Chem 2022-00-22

...SOS1 inhibitor BI3406. In summary, we developed new SOS1 degraders and demonstrated SOS1 degradation as a feasible thera...

Ullah(A),Dutta(D),Fliegel(L) Mol Cell Biochem 2016-04-00

...SOS1, in expression of the protein in S. pombe. We expressed full-length SOS1 and SOS1 shortened at the C-terminus and e...