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GSR

Gene name:glutathione-disulfide reductase

...GSR依赖NADPH作为辅因子,通过其活性位点的半胱氨酸残基催化GSSG还原反应。GSR广泛分布于各种组织中,尤其在肝脏、红细胞和大脑中表达较高。GSR基因突变可能导致酶活性降低或丧失,从而引发氧化应激增加、GSH水平下降,与多种疾病相关,...

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