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RARB

Gene name:retinoic acid receptor beta

...RARB的突变或表观遗传沉默(如启动子区甲基化)会导致其功能丧失,与多种癌症(如肺癌、乳腺癌、前列腺癌)的发生发展密切相关。RARB过表达可抑制肿瘤细胞增殖并诱导分化,而表达降低则可能促进肿瘤进展和转移。此外,RARB在神经系统发育中起关键...

RARB-AS1

Gene name:RARB antisense RNA 1

...RARB)基因相邻并反向转录。作为RARB基因的反义RNA,RARB-AS1通过表观遗传调控、转录干扰或RNA稳定性调节等方式影响RARB的表达。RARB属于核受体超家族,在细胞分化、增殖和凋亡中起关键作用,特别是在视黄酸信号通路中。RAR...

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