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PMID: 14681482 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The mouse Gene Expression Database (GXD): updates and enhancements.

Nucleic acids research ·Vol. 32 ·No. Database issue ·2004-01-01 ·Pages D568-71

Hill DP, Begley DA, Finger JH, Hayamizu TF, McCright IJ, Smith CM, Beal JS, Corbani LE, Blake JA, Eppig JT, Kadin JA, Richardson JE, Ringwald M

Abstract

The Gene Expression Database (GXD) is a community resource for gene expression information in the laboratory mouse. By collecting and integrating different types of expression data, GXD provides information about expression profiles in different mouse strains and mutants. Participation in the Gene Ontology (GO) project classifies genes and gene products with regard to molecular functions, biological processes, and cellular components. Integration with other Mouse Genome Informatics (MGI) databases places the gene expression information in the context of mouse genetic, genomic and phenotypic information. The integration of these types of information enables valuable insights into the molecular biology that underlies development and disease. The utility of GXD has been improved by the daily addition of new data and through the implementation of new query and display features. These improvements make it easier for users to interrogate and visualize expression data in the context of their specific needs. GXD is accessible through the MGI website at http://www.informatics.jax.org/ or directly at http://www. informatics.jax.org/menus/expression_menu.shtml.

MeSH Terms
Animals Databases, Genetic Gene Expression Profiling Genome Genomics Information Storage and Retrieval Internet Mice/classification,genetics
Authors & Affiliations
13 authors, click to expand affiliations / ORCID
Hill David P
The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Begley Dale A
Finger Jacqueline H
Hayamizu Terry F
McCright Ingeborg J
Smith Constance M
Beal Jon S
Corbani Lori E
Blake Judith A
Eppig Janan T
Kadin James A
Richardson Joel E
Ringwald Martin
References (24)
24 references, click to expand
  1. The Mouse Gene Expression Database (GXD).
    Nucleic Acids Res. 2001 Jan 1;29(1):98-101 PMID: 11125060
  2. Human chromosome 21 gene expression atlas in the mouse.
    Nature. 2002 Dec 5;420(6915):582-6 PMID: 12466854
  3. A database for mouse development.
    Science. 1994 Sep 30;265(5181):2033-4 PMID: 8091224
  4. The Protein Data Bank.
    Nucleic Acids Res. 2000 Jan 1;28(1):235-42 PMID: 10592235
  5. The ARKdb: genome databases for farmed and other animals.
    Nucleic Acids Res. 2001 Jan 1;29(1):106-10 PMID: 11125062
  6. Connecting sequence and biology in the laboratory mouse.
    Genome Res. 2003 Jun;13(6B):1505-19 PMID: 12819150
  7. A gene expression map of human chromosome 21 orthologues in the mouse.
    Nature. 2002 Dec 5;420(6915):586-90 PMID: 12466855
  8. The Gene Ontology (GO) database and informatics resource.
    Nucleic Acids Res. 2004 Jan 1;32(Database issue):D258-61 PMID: 14681407
  9. GenBank.
    Nucleic Acids Res. 2003 Jan 1;31(1):23-7 PMID: 12519940
  10. The Mouse Genome Database (MGD): integrating biology with the genome.
    Nucleic Acids Res. 2004 Jan 1;32(Database issue):D476-81 PMID: 14681461
  11. The InterPro database, an integrated documentation resource for protein families, domains and functional sites.
    Nucleic Acids Res. 2001 Jan 1;29(1):37-40 PMID: 11125043
  12. Initial sequencing and comparative analysis of the mouse genome.
    Nature. 2002 Dec 5;420(6915):520-62 PMID: 12466850
  13. MGD: the Mouse Genome Database.
    Nucleic Acids Res. 2003 Jan 1;31(1):193-5 PMID: 12519980
  14. Rat Genome Database (RGD): mapping disease onto the genome.
    Nucleic Acids Res. 2002 Jan 1;30(1):125-8 PMID: 11752273
  15. Database resources of the National Center for Biotechnology.
    Nucleic Acids Res. 2003 Jan 1;31(1):28-33 PMID: 12519941
  16. The TIGR Gene Indices: analysis of gene transcript sequences in highly sampled eukaryotic species.
    Nucleic Acids Res. 2001 Jan 1;29(1):159-64 PMID: 11125077
  17. The mouse gene expression database GXD
    Semin Cell Dev Biol. 1997 Oct;8(5):489-97 PMID: 9441954
  18. Extension and integration of the gene ontology (GO): combining GO vocabularies with external vocabularies.
    Genome Res. 2002 Dec;12(12):1982-91 PMID: 12466303
  19. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
    Nature. 2002 Dec 5;420(6915):563-73 PMID: 12466851
  20. An internet-accessible database of mouse developmental anatomy based on a systematic nomenclature.
    Mech Dev. 1998 Jun;74(1-2):111-20 PMID: 9651497
  21. GXD: a Gene Expression Database for the laboratory mouse: current status and recent enhancements. The Gene Expresison Database group.
    Nucleic Acids Res. 2000 Jan 1;28(1):115-9 PMID: 10592197
  22. GXD: a gene expression database for the laboratory mouse. The Gene Expression Database Group.
    Nucleic Acids Res. 1999 Jan 1;27(1):106-12 PMID: 9847152
  23. The Ensembl genome database project.
    Nucleic Acids Res. 2002 Jan 1;30(1):38-41 PMID: 11752248
  24. The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003.
    Nucleic Acids Res. 2003 Jan 1;31(1):365-70 PMID: 12520024
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
Published
2004-01-01
Pages
D568-71
Language
English
Region
England
NLM ID
0411011
PMCID
PMC308803
Subset
IM
Grants
NICHD NIH HHS · HD33745 · United States
NHGRI NIH HHS · U41 HG002273 · United States
NICHD NIH HHS · R01 HD033745 · United States
NHGRI NIH HHS · R01 HG002273 · United States
NHGRI NIH HHS · HG02273 · United States
NHGRI NIH HHS · P41 HG002273 · United States
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