Home LiteratureArticle Details
PMID: 15170476 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

Plants: the latest model system for G-protein research.

EMBO reports ·Vol. 5 ·No. 6 ·2004-06-00 ·Pages 572-8

Jones AM, Assmann SM

Abstract

In humans, heterotrimeric G proteins couple stimulus perception by G-protein-coupled receptors (GPCRs) with numerous downstream effectors. By contrast, despite great complexity in their signal-transduction attributes, plants have a simpler repertoire of G-signalling components. Nonetheless, recent studies on Arabidopsis thaliana have shown the importance of plant G-protein signalling in such fundamental processes as cell proliferation, hormone perception and ion-channel regulation.

MeSH Terms
Cell Division Genome, Human Genome, Plant Heterotrimeric GTP-Binding Proteins/genetics,metabolism Humans Ion Channels/metabolism Plant Proteins/genetics,metabolism Plants/metabolism Signal Transduction
Chemicals
Ion Channels Plant Proteins Heterotrimeric GTP-Binding Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Jones Alan M
Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA. [email protected]
Assmann Sarah M
References (66)
66 references, click to expand
  1. Molecular identification of cytosolic, patatin-related phospholipases A from Arabidopsis with potential functions in plant signal transduction.
    Plant Physiol. 2002 Sep;130(1):90-101 PMID: 12226489
  2. A seven-transmembrane RGS protein that modulates plant cell proliferation.
    Science. 2003 Sep 19;301(5640):1728-31 PMID: 14500984
  3. Cloning and direct G-protein regulation of phospholipase D from tobacco.
    Biochim Biophys Acta. 2001 Feb 26;1530(2-3):172-83 PMID: 11239820
  4. Activation of a plant plasma membrane Ca2+ channel by TGalpha1, a heterotrimeric G protein alpha-subunit homologue.
    FEBS Lett. 1998 Mar 6;424(1-2):17-21 PMID: 9537507
  5. Molecular cloning and characterization of GPA1, a G protein alpha subunit gene from Arabidopsis thaliana.
    Proc Natl Acad Sci U S A. 1990 May;87(10):3821-5 PMID: 2111018
  6. Rice dwarf mutant d1, which is defective in the alpha subunit of the heterotrimeric G protein, affects gibberellin signal transduction.
    Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11638-43 PMID: 11027362
  7. Isolation of cDNAs encoding guanine nucleotide-binding protein beta-subunit homologues from maize (ZGB1) and Arabidopsis (AGB1).
    Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9554-8 PMID: 7937804
  8. Structure and regulation of voltage-gated Ca2+ channels.
    Annu Rev Cell Dev Biol. 2000;16:521-55 PMID: 11031246
  9. Arabidopsis phospholipase Dalpha1 interacts with the heterotrimeric G-protein alpha-subunit through a motif analogous to the DRY motif in G-protein-coupled receptors.
    J Biol Chem. 2004 Jan 16;279(3):1794-800 PMID: 14594812
  10. A reevaluation of the role of the heterotrimeric G protein in coupling light responses in Arabidopsis.
    Plant Physiol. 2003 Apr;131(4):1623-7 PMID: 12692321
  11. Structure and function of heterotrimeric G proteins in plants.
    Plant Cell Physiol. 2001 Aug;42(8):789-94 PMID: 11522903
  12. A higher plant seven-transmembrane receptor that influences sensitivity to cytokinins.
    Curr Biol. 1998 Mar 12;8(6):315-24 PMID: 9512416
  13. G protein specificity: traffic direction required.
    Cell Signal. 2002 May;14(5):407-18 PMID: 11882385
  14. Molecular cloning and characterization of a cDNA for the alpha subunit of a G protein from rice.
    Plant Cell Physiol. 1995 Mar;36(2):353-9 PMID: 7767602
  15. Seven-transmembrane-spanning receptors and heart function.
    Nature. 2002 Jan 10;415(6868):206-12 PMID: 11805844
  16. Characterization of heterotrimeric G protein complexes in rice plasma membrane.
    Plant J. 2004 Apr;38(2):320-31 PMID: 15078334
  17. Molecular phylogeny and evolution of the plant-specific seven-transmembrane MLO family.
    J Mol Evol. 2003 Jan;56(1):77-88 PMID: 12569425
  18. Nod factors activate both heterotrimeric and monomeric G-proteins in Vigna unguiculata (L.) Walp.
    Planta. 2003 Feb;216(4):674-85 PMID: 12569410
  19. Rhizobium nod factor signaling. Evidence for a g protein-mediated transduction mechanism
    Plant Cell. 1998 May;10(5):659-72 PMID: 9596628
  20. Phosphatidylinositol 3- and 4-phosphate are required for normal stomatal movements.
    Plant Cell. 2002 Oct;14(10):2399-412 PMID: 12368494
  21. GCR1 can act independently of heterotrimeric G-protein in response to brassinosteroids and gibberellins in Arabidopsis seed germination.
    Plant Physiol. 2004 Jun;135(2):907-15 PMID: 15181210
  22. Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins.
    Nature. 2003 Jun 5;423(6940):651-4 PMID: 12789341
  23. Evidence for Edg-3 receptor-mediated activation of I(K.ACh) by sphingosine-1-phosphate in human atrial cardiomyocytes.
    Mol Pharmacol. 2000 Aug;58(2):449-54 PMID: 10908314
  24. The Arabidopsis cupin domain protein AtPirin1 interacts with the G protein alpha-subunit GPA1 and regulates seed germination and early seedling development.
    Plant Cell. 2003 Jul;15(7):1578-90 PMID: 12837948
  25. Activation of Plant Plasma Membrane Ca2+-Permeable Channels by Race-Specific Fungal Elicitors.
    Plant Physiol. 1997 Jan;113(1):269-279 PMID: 12223606
  26. Physiological regulation of G protein-linked signaling.
    Physiol Rev. 1999 Oct;79(4):1373-430 PMID: 10508237
  27. Characterization of the putative alpha subunit of a heterotrimeric G protein in rice.
    Plant Mol Biol. 1997 Jul;34(4):563-72 PMID: 9247538
  28. Seven-transmembrane receptors.
    Nat Rev Mol Cell Biol. 2002 Sep;3(9):639-50 PMID: 12209124
  29. Biochemical characteristics of a rice (Oryza sativa L., IR36) G-protein alpha-subunit expressed in Escherichia coli.
    Biochem J. 1997 May 15;324 ( Pt 1):273-81 PMID: 9164867
  30. GTP-binding proteins in plants: new members of an old family.
    Plant Mol Biol. 1994 Dec;26(5):1611-36 PMID: 7858207
  31. G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK.
    Neuron. 2002 Jan 3;33(1):87-99 PMID: 11779482
  32. Sphingosine-1-phosphate: an enigmatic signalling lipid.
    Nat Rev Mol Cell Biol. 2003 May;4(5):397-407 PMID: 12728273
  33. G-protein-coupled signaling in Arabidopsis.
    Curr Opin Plant Biol. 2002 Oct;5(5):402-7 PMID: 12183178
  34. G beta gamma and KACh: old story, new insights.
    Sci STKE. 2003 Aug 5;2003(194):PE32 PMID: 12902568
  35. Completing the heterotrimer: isolation and characterization of an Arabidopsis thaliana G protein gamma-subunit cDNA.
    Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14784-8 PMID: 11121078
  36. GCR1, the putative Arabidopsis G protein-coupled receptor gene is cell cycle-regulated, and its overexpression abolishes seed dormancy and shortens time to flowering.
    Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4736-41 PMID: 11930019
  37. Rice gibberellin-insensitive dwarf mutant gene Dwarf 1 encodes the alpha-subunit of GTP-binding protein.
    Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10284-9 PMID: 10468600
  38. Analysis of the small GTPase gene superfamily of Arabidopsis.
    Plant Physiol. 2003 Mar;131(3):1191-208 PMID: 12644670
  39. Identification of a novel protein with guanylyl cyclase activity in Arabidopsis thaliana.
    J Biol Chem. 2003 Feb 21;278(8):6490-4 PMID: 12482758
  40. Cloning of a putative G-protein-coupled receptor from Arabidopsis thaliana.
    Eur J Biochem. 1997 Oct 15;249(2):415-20 PMID: 9370348
  41. Overexpression of the heterotrimeric G-protein alpha-subunit enhances phytochrome-mediated inhibition of hypocotyl elongation in Arabidopsis.
    Plant Cell. 2001 Jul;13(7):1639-52 PMID: 11449056
  42. The G-protein-coupled receptor GCR1 regulates DNA synthesis through activation of phosphatidylinositol-specific phospholipase C.
    Plant Physiol. 2003 Oct;133(2):571-9 PMID: 12972659
  43. Heterotrimeric and unconventional GTP binding proteins in plant cell signaling.
    Plant Cell. 2002;14 Suppl:S355-73 PMID: 12045288
  44. Molecular basis for interactions of G protein betagamma subunits with effectors.
    Science. 1998 May 22;280(5367):1271-4 PMID: 9596582
  45. Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C.
    Plant Physiol. 2002 Sep;130(1):22-46 PMID: 12226484
  46. The pharmacology of phosducin.
    Pharmacol Res. 2001 Jan;43(1):1-10 PMID: 11207059
  47. Expansion of the receptor-like kinase/Pelle gene family and receptor-like proteins in Arabidopsis.
    Plant Physiol. 2003 Jun;132(2):530-43 PMID: 12805585
  48. The heterotrimeric G protein alpha subunit acts upstream of the small GTPase Rac in disease resistance of rice.
    Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13307-12 PMID: 12237405
  49. The beta-subunit of the Arabidopsis G protein negatively regulates auxin-induced cell division and affects multiple developmental processes.
    Plant Cell. 2003 Feb;15(2):393-409 PMID: 12566580
  50. A mutant Arabidopsis heterotrimeric G-protein beta subunit affects leaf, flower, and fruit development.
    Plant Cell. 2001 Dec;13(12):2631-41 PMID: 11752377
  51. Molecular analyses of the Arabidopsis TUBBY-like protein gene family.
    Plant Physiol. 2004 Apr;134(4):1586-97 PMID: 15064372
  52. Phospholipase D in hormonal and stress signaling.
    Curr Opin Plant Biol. 2002 Oct;5(5):408-14 PMID: 12183179
  53. Drought-induced guard cell signal transduction involves sphingosine-1-phosphate.
    Nature. 2001 Mar 29;410(6828):596-9 PMID: 11279499
  54. G-protein mediated gating of inward-rectifier K+ channels.
    Eur J Biochem. 2000 Oct;267(19):5830-6 PMID: 10998041
  55. Role of a heterotrimeric G protein in regulation of Arabidopsis seed germination.
    Plant Physiol. 2002 Jun;129(2):897-907 PMID: 12068128
  56. Immunological detection of potential signal-transduction proteins expressed during wheat somatic tissue culture.
    Plant Physiol. 1997 Mar;113(3):801-7 PMID: 9085574
  57. The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling.
    Plant Cell. 2004 Jun;16(6):1616-32 PMID: 15155892
  58. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling.
    Pharmacol Rev. 2001 Mar;53(1):1-24 PMID: 11171937
  59. Modulation of cell proliferation by heterotrimeric G protein in Arabidopsis.
    Science. 2001 Jun 15;292(5524):2066-9 PMID: 11408654
  60. cAMP acts as a second messenger in pollen tube growth and reorientation.
    Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10481-6 PMID: 11517303
  61. Arabidopsis thaliana 'extra-large GTP-binding protein' (AtXLG1): a new class of G-protein.
    Plant Mol Biol. 1999 May;40(1):55-64 PMID: 10394945
  62. Isolation of a novel G-protein gamma-subunit from Arabidopsis thaliana and its interaction with Gbeta.
    Biochim Biophys Acta. 2001 Aug 30;1520(2):147-53 PMID: 11513956
  63. G-protein- and cAMP-dependent L-channel gating modulation: a manyfold system to control calcium entry in neurosecretory cells.
    Pflugers Arch. 2001 Sep;442(6):801-13 PMID: 11680611
  64. Molecular characterization of cDNAs encoding G protein alpha and beta subunits and study of their temporal and spatial expression patterns in Nicotiana plumbaginifolia Viv.
    Biochim Biophys Acta. 2000 Apr 25;1491(1-3):143-60 PMID: 10760577
  65. G protein regulation of ion channels and abscisic acid signaling in Arabidopsis guard cells.
    Science. 2001 Jun 15;292(5524):2070-2 PMID: 11408655
  66. Polypeptide hormones.
    Plant Cell. 2002;14 Suppl:S251-64 PMID: 12045281
Article Info
Journal
EMBO reports
Abbr.
EMBO Rep
ISSN
1469-221X
Published
2004-06-00
Pages
572-8
Language
English
Region
England
NLM ID
100963049
PMCID
PMC1299082
Subset
IM
Grants
NIGMS NIH HHS · R01 GM065989 · United States
NIGMS NIH HHS · GM65989-01 · United States
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]