Polymorphix: a sequence polymorphism database.

Nucleic acids research ·Vol. 33 ·No. Database issue ·2005-01-01 ·Pages D481-4

Bazin E, Duret L, Penel S, Galtier N

Abstract

Within-species sequence variation data are of special interest since they contain information about recent population/species history, and the molecular evolutionary forces currently in action in natural populations. These data, however, are presently dispersed within generalist databases, and are difficult to access. To solve this problem, we have developed Polymorphix, a database dedicated to sequence polymorphism. It contains within-species homologous sequence families built using EMBL/GenBank under suitable similarity and bibliographic criteria. Polymorphix is an ACNUC structured database allowing both simple and complex queries for population genomic studies. Alignments within families as well as phylogenetic trees can be download. When available, outgroups are included in the alignment. Polymorphix contains sequences from the nuclear, mitochondrial and chloroplastic genomes of every eukaryote species represented in EMBL. It can be accessed by a web interface (http://pbil.univ-lyon1.fr/polymorphix/query.php).

MeSH Terms

Animals Databases, Nucleic Acid Genomics Humans Phylogeny Polymorphism, Genetic Sequence Alignment Sequence Homology, Nucleic Acid User-Computer Interface

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Bazin Eric

Laboratoire Génome Populations Interactions Adaptation, Unité Mixte de Recherche No. 5171 (UMR UM2-IFREMER-CNRS), Université de Montpellier 2, 34095 Montpellier Cedex 5, France. [email protected]

Duret Laurent

Penel Simon

Galtier Nicolas

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

1362-4962

DOI

10.1093/nar/gki076

[email protected]

Published

2005-01-01

Pages

D481-4

Language

English

Region

England

NLM ID

0411011

PMCID

PMC540030

Subset

External Links

PubMed source DOI: 10.1093/nar/gki076 PMC Full Text View journal details

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