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PMID: 15956661 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Contrasting patterns of polymorphism and divergence on the Z chromosome and autosomes in two Ficedula flycatcher species.

Genetics ·Vol. 171 ·No. 4 ·2005-12-00 ·Pages 1861-73

Borge T, Webster MT, Andersson G, Saetre GP

Abstract

In geographic areas where pied and collared flycatchers (Ficedula hypoleuca and F. albicollis) breed in sympatry, hybridization occurs, leading to gene flow (introgression) between the two recently diverged species. Notably, while such introgression is observable at autosomal loci it is apparently absent at the Z chromosome, suggesting an important role for genes on the Z chromosome in creating reproductive isolation during speciation. To further understand the role of Z-linked loci in the formation of new species, we studied genetic variation of the two species from regions where they live in allopatry. We analyzed patterns of polymorphism and divergence in introns from 9 Z-linked and 23 autosomal genes in pied and collared flycatcher males. Average variation on the Z chromosome is greatly reduced compared to neutral expectations based on autosomal diversity in both species. We also observe significant heterogeneity between patterns of polymorphism and divergence at Z-linked loci and a relative absence of polymorphisms that are shared by the two species on the Z chromosome compared to the autosomes. We suggest that these observations may indicate the action of recurrent selective sweeps on the Z chromosome during the evolution of the two species, which may be caused by sexual selection acting on Z-linked genes. Alternatively, reduced variation on the Z chromosome could result from substantially higher levels of introgression at autosomal than at Z-linked loci or from a complex demographic history, such as a population bottleneck.

MeSH Terms
Animals Base Sequence Cluster Analysis Evolution, Molecular Genetic Speciation Genetics, Population Haplotypes/genetics Italy Male Molecular Sequence Data Polymorphism, Genetic Selection, Genetic Sequence Analysis, DNA Sex Chromosomes/genetics Songbirds/genetics Spain
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Borge Thomas
Department of Biology, Centre for Ecological and Evolutionary Synthesis, University of Oslo, N-0316 Oslo. Norway.
Webster Matthew T
Andersson Gunilla
Saetre Glenn-Peter
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1534/genetics.105.045120
Published
2005-12-00
Epub
2005-00-14
Pages
1861-73
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1456110
Subset
IM
Databases
GENBANK
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PubMed source DOI: 10.1534/genetics.105.045120 PMC Full Text View journal details
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