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PMID: 18076328 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

DNA transposons and the evolution of eukaryotic genomes.

Annual review of genetics ·Vol. 41 ·2007-00-00 ·Pages 331-68

Feschotte C, Pritham EJ

Abstract

Transposable elements are mobile genetic units that exhibit broad diversity in their structure and transposition mechanisms. Transposable elements occupy a large fraction of many eukaryotic genomes and their movement and accumulation represent a major force shaping the genes and genomes of almost all organisms. This review focuses on DNA-mediated or class 2 transposons and emphasizes how this class of elements is distinguished from other types of mobile elements in terms of their structure, amplification dynamics, and genomic effect. We provide an up-to-date outlook on the diversity and taxonomic distribution of all major types of DNA transposons in eukaryotes, including Helitrons and Mavericks. We discuss some of the evolutionary forces that influence their maintenance and diversification in various genomic environments. Finally, we highlight how the distinctive biological features of DNA transposons have contributed to shape genome architecture and led to the emergence of genetic innovations in different eukaryotic lineages.

MeSH Terms
Biological Evolution DNA/genetics DNA Transposable Elements Eukaryotic Cells Genome
Chemicals
DNA Transposable Elements DNA
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Feschotte Cédric
Department of Biology, University of Texas, Arlington, TX 76019, USA. [email protected]
Pritham Ellen J
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Article Info
Journal
Annual review of genetics
Abbr.
Annu Rev Genet
ISSN
0066-4197
DOI
10.1146/annurev.genet.40.110405.090448
Email
[email protected]
Published
2007-00-00
Pages
331-68
Language
English
Region
United States
NLM ID
0117605
PMCID
PMC2167627
Subset
IM
Grants
NIGMS NIH HHS · R01 GM077582 · United States
NIGMS NIH HHS · R01 GM077582-01A1 · United States
NIAID NIH HHS · R01 AI 068908-01 · United States
NIGMS NIH HHS · R01 GM 77582-01 · United States
External Links
PubMed source DOI: 10.1146/annurev.genet.40.110405.090448 PMC Full Text View journal details
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